Tanabe Hiroshi, Abe Noriyuki, Anzawa Kazushi
Department of Dermatology, Tenri Hospital, Tenri 632-8552, Japan.
Department of Laboratory Medicine, Tenri Hospital, Tenri 632-8552, Japan.
J Fungi (Basel). 2023 Nov 19;9(11):1122. doi: 10.3390/jof9111122.
, an anthropophilic dermatophyte, can cause dermatophytosis in humans and animals with rising zoonotic infections through pets, primarily in Europe. Dermatophytosis from is often misdiagnosed due to its inflammatory symptoms. We report a case of from var. in a Japanese woman, contracted from pet Czech degus.
The 40-year-old patient developed neck papules resembling acne. Initial treatment with topical antibiotics and steroids exacerbated the rash. Fungal elements were not detected by direct potassium hydroxide examination. Skin biopsy confirmed fungal elements in the and hair follicles, and was diagnosed. Oral terbinafine 125 mg was initiated without topical agents. Erythematous papules appeared on her limbs, determined as a trichophytid reaction. After two months, her skin improved significantly. Fungal culture identified var. colonies with a yellowish hue. Mating tests classified the strain as Americano-European race (-) with genotype. This was diagnosed as from var. , likely transmitted from pet Czech degus.
The incidence rate of pet-transmitted cutaneous fungal infections may increase in Japan with the trend to keep exotic pets. Dermatologists must recognize dermatophytosis clinical features from anthropophilic dermatophytes to prevent misdiagnosis and understand evolving nomenclature and pathogenesis.
亲人性皮肤癣菌可导致人和动物的皮肤癣菌病，且通过宠物传播的人畜共患感染呈上升趋势，主要在欧洲。由于其炎症症状，来自亲人性皮肤癣菌的皮肤癣菌病常被误诊。我们报告一例来自亲人性须癣毛癣菌豚鼠变种的病例，该病例发生在一名日本女性身上，是通过宠物捷克天竺鼠感染的。
这位40岁的患者出现了类似痤疮的颈部丘疹。最初使用外用抗生素和类固醇进行治疗使皮疹加重。直接氢氧化钾检查未检测到真菌成分。皮肤活检证实了在表皮和毛囊中有真菌成分，从而确诊。在未使用外用药物的情况下开始口服125毫克特比萘芬。她的四肢出现了红斑丘疹，确定为癣菌疹反应。两个月后，她的皮肤有了显著改善。真菌培养鉴定出有淡黄色色调的亲人性须癣毛癣菌豚鼠变种菌落。交配试验将该菌株分类为具有V基因型的欧美种族（-）。这被诊断为亲人性须癣毛癣菌豚鼠变种，可能是通过宠物捷克天竺鼠传播的。
随着饲养外来宠物的趋势，在日本宠物传播的皮肤真菌感染发病率可能会增加。皮肤科医生必须认识到亲人性皮肤癣菌引起的皮肤癣菌病的临床特征，以防止误诊，并了解不断演变的命名法和发病机制。
