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分枝杆菌心内膜炎在心导管术后:病例报告及 25 例病例回顾(2001-2023 年)。

Mycobacterium abscessus endocarditis post cardiac cathetrisation-a case report and review of 25 cases (2001-2023).

机构信息

Department of Microbiology, Velammal Medical College Hospital and Research Institute, Madurai, India.

Department of Cardiology, Velammal Medical College Hospital and Research Institute, Madurai, India.

出版信息

Indian J Med Microbiol. 2024 Jan-Feb;47:100517. doi: 10.1016/j.ijmmb.2023.100517. Epub 2023 Nov 26.

DOI:10.1016/j.ijmmb.2023.100517
PMID:38000620
Abstract

47 year male underwent percutaneous transluminal coronary angioplasty elsewhere, developed fever after two days, and treated empirically in various hospitals for the subsequent two months. Echocardiography showed vegetation in aortic valve and blood cultures were negative. He was then diagnosed as a case of endocarditis due to M. abscessus in our centre by repeated positive blood cultures. After treatment with Imipenem, Amikacin and clarithromycin in the background of pancytopenia, patient was discharged with advice to continue antibiotics and planned for aortic valve replacement. Patient was noncompliant to treatment, readmitted with worsening symptoms, developed multiorgan failure and subsequently died of infection.

摘要

一位 47 岁男性曾在其他地方接受过经皮腔内冠状动脉血管成形术,术后两天出现发热,随后在多家医院接受经验性治疗两个月。超声心动图显示主动脉瓣有赘生物,血培养阴性。后来,由于血培养反复阳性,我们中心诊断他为脓肿分枝杆菌引起的心内膜炎。在全血细胞减少的背景下,他使用亚胺培南、阿米卡星和克拉霉素治疗后出院,出院时建议继续使用抗生素并计划进行主动脉瓣置换术。该患者不遵医嘱治疗,症状恶化后再次入院,出现多器官衰竭,随后因感染死亡。

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