Lau Adrian, Prout Tyler, Malabanan Alan, Szalat Auryan, Krueger Diane, Tanner S Bobo, Rosen Harold, Shuhart Christopher
Division of Endocrinology and Metabolism, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.
Radiology Department, University of Wisconsin, Madison, WI, United States.
J Clin Densitom. 2024 Jan-Mar;27(1):101439. doi: 10.1016/j.jocd.2023.101439. Epub 2023 Oct 31.
Incomplete atypical femur fractures (iAFFs) are associated with the long-term use of anti-resorptive therapies. Although X-rays are typically used to screen for iAFFs, images from dual-energy X-ray absorptiometry (DXA) offer an alternate method for detecting iAFFs. Although a previous 2019 ISCD Official Position on this subject exists, our task force aimed to update the literature review and to propose recommendations on reporting findings related to iAFFs that may be observed on DXA images. The task force recommended that full-length femur imaging (FFI) from DXA can be used as a screening tool for iAFFs. The presence of focal lateral cortical thickening and transverse lucencies should be reported, if identified on the FFI. This task force proposed a classification system to determine the likelihood of an iAFF, based on radiographic features seen on the FFI. Lastly, the task force recommended that the clinical assessment of prodromal symptoms (pain) is not required for the assessment of FFI.
不完全性非典型股骨骨折(iAFFs)与长期使用抗吸收疗法有关。虽然X射线通常用于筛查iAFFs,但双能X射线吸收法(DXA)图像提供了一种检测iAFFs的替代方法。尽管此前在2019年已有国际临床骨密度学会(ISCD)关于该主题的官方立场,但我们的特别工作组旨在更新文献综述,并就报告DXA图像上可能观察到的与iAFFs相关的结果提出建议。特别工作组建议,DXA的全长股骨成像(FFI)可作为iAFFs的筛查工具。如果在FFI上发现,应报告局灶性外侧皮质增厚和横向透亮区的存在。该特别工作组提出了一个分类系统,根据FFI上看到的影像学特征来确定iAFF的可能性。最后,特别工作组建议,评估FFI时不需要对前驱症状(疼痛)进行临床评估。