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一名16岁男孩在新冠病毒病病程中发生的缺血性中风

Ischemic Stroke in the Course of COVID-19 in a 16-Year-Old Boy.

作者信息

Syzdoł Bartłomiej, Rzewuska Anna Maria, Sielwanowska Wiktoria, Żybowska Monika, Wilczek Natalia Anna, Woźniak Magdalena Maria

机构信息

Students' Scientific Society at the Department of Pediatric Radiology, Medical University of Lublin, 20-059 Lublin, Poland.

Students' Research Group at the Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, 20-059 Lublin, Poland.

出版信息

J Clin Med. 2023 Nov 7;12(22):6963. doi: 10.3390/jcm12226963.

Abstract

The SARS-CoV-2 virus that causes COVID-19 disease is still evolving and, despite the end of the acute phase of the pandemic, still poses a risk to public health. One of the very rare complications, occurring in less than 1% of children, is multisystem inflammatory syndrome in children (MISC). Due to the risk of thromboembolic complications as well as cardiac problems, MISC carries a number of life-threatening complications. We report a case of a 16-year-old boy who was hospitalized due to general weakness, fever, conjunctivitis, vomiting and diarrhoea. In view of the mother's positive result of the SARS-CoV-2 test, the teenager underwent numerous laboratory tests. Taking into account the critical condition of the patient, anticoagulant and antipyretic treatment, steroids and IVIG were added. During hospitalisation, alarming symptoms occurred, including dysarthria, drooping corner of the mouth and muscle weakness on the right side. The magnetic resonance imaging showed changes characteristic of ischemic stroke. Further studies are needed to assess possible thrombotic complications in children after SARS-CoV-2 infection, and specialists should be more vigilant in paediatric patients presenting with such symptoms.

摘要

导致新冠肺炎疾病的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)仍在演变,尽管大流行的急性期已经结束,但仍然对公众健康构成风险。儿童多系统炎症综合征(MISC)是一种非常罕见的并发症,在不到1%的儿童中出现。由于存在血栓栓塞并发症以及心脏问题的风险,MISC会引发许多危及生命的并发症。我们报告了一例16岁男孩的病例,该男孩因全身无力、发热、结膜炎、呕吐和腹泻而住院。鉴于其母亲的SARS-CoV-2检测结果呈阳性,该青少年接受了多项实验室检查。考虑到患者的危急状况,添加了抗凝和退热治疗、类固醇和静脉注射免疫球蛋白。住院期间出现了令人担忧的症状,包括构音障碍、口角下垂和右侧肌肉无力。磁共振成像显示出缺血性中风的特征性变化。需要进一步研究以评估SARS-CoV-2感染后儿童可能出现的血栓并发症,并且专家应对出现此类症状的儿科患者更加警惕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a65/10672380/84bf16fbfbe9/jcm-12-06963-g001.jpg

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