Han Jasmine J, Song Hannah A, Pierson Sarah L, Shen-Gunther Jane, Xia Qingqing
Division of Gynecologic Oncology, Department of Gynecologic Surgery and Obstetrics, Department of Clinical Investigation, Brooke Army Medical Center, San Antonio, TX 78234, USA.
Department of Bioengineering, University of California, Los Angeles, CA 90024, USA.
Microorganisms. 2023 Oct 24;11(11):2618. doi: 10.3390/microorganisms11112618.
The recent pandemic caused by SARS-CoV-2 affected the global population, resulting in a significant loss of lives and global economic deterioration. COVID-19 highlighted the importance of public awareness and science-based decision making, and exposed global vulnerabilities in preparedness and response systems. Emerging and re-emerging viral outbreaks are becoming more frequent due to increased international travel and global warming. These viral outbreaks impose serious public health threats and have transformed national strategies for pandemic preparedness with global economic consequences. At the molecular level, viral mutations and variations are constantly thwarting vaccine efficacy, as well as diagnostic, therapeutic, and prevention strategies. Here, we discuss viral infectious diseases that were epidemic and pandemic, currently available treatments, and surveillance measures, along with their limitations.
由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引发的近期大流行影响了全球人口,导致大量人员死亡和全球经济衰退。2019冠状病毒病(COVID-19)凸显了公众意识和基于科学的决策的重要性,并暴露了全球防范和应对系统中的脆弱性。由于国际旅行增加和全球变暖,新出现和再次出现的病毒爆发变得更加频繁。这些病毒爆发构成了严重的公共卫生威胁,并改变了各国的大流行防范战略,造成了全球经济后果。在分子层面,病毒突变和变异不断削弱疫苗效力以及诊断、治疗和预防策略。在此,我们讨论曾经流行和大流行的病毒传染病、目前可用的治疗方法以及监测措施,以及它们的局限性。