小儿睾丸生殖细胞肿瘤手术的关键要素。

Critical elements of pediatric testicular germ cell tumors surgery.

作者信息

Saltzman Amanda F, Hensley Patrick, Ross Jonathan, Woo Lynn, Billmire Deborah, Rescorla Frederick, Puri Dhruv, Patel Sunil, Pierorazio Phillip, Bagrodia Aditya, Cary Clint, Cost Nicholas G

机构信息

Department of Urology, University of Kentucky, Lexington, KY, USA.

Department of Urology, Rush University, Chicago, IL, USA.

出版信息

Semin Pediatr Surg. 2023 Oct;32(5):151343. doi: 10.1016/j.sempedsurg.2023.151343. Epub 2023 Nov 17.

DOI:10.1016/j.sempedsurg.2023.151343

PMID:38006835

Abstract

Children, adolescents and young adults with testicular germ cell tumors require appropriate surgical care to insure excellent outcomes. This article presents the most critical elements, and their basis in evidence, for surgery in this population. Specifically, the importance of inguinal radical orchiectomy for malignant tumors, partial orchiectomy for prepubertal tumors and normal serum tumor markers, and the appropriate use of post-chemotherapy retroperitoneal lymph node dissection in those with residual retroperitoneal masses.

摘要

患有睾丸生殖细胞肿瘤的儿童、青少年和年轻成年人需要适当的手术治疗以确保良好的治疗效果。本文介绍了针对该人群手术治疗的最关键要素及其证据基础。具体而言，对于恶性肿瘤进行腹股沟根治性睾丸切除术、对于青春期前肿瘤且血清肿瘤标志物正常进行睾丸部分切除术，以及对有残留腹膜后肿块的患者适当应用化疗后腹膜后淋巴结清扫术的重要性。