Ramirez-Lassepas M, Cipolle R J, Bjork R J, Kowitz J, Snyder B D, Weber J C, Stein S D
Arch Neurol. 1987 Jan;44(1):87-9. doi: 10.1001/archneur.1987.00520130067019.
Diagnosis of embolic stroke is based on identification of a source of embolus (SOE) and on neurologic symptoms acknowledged as "clinical criteria." To test the validity of these criteria, we analyzed the symptoms at onset in 193 patients hospitalized after acute cerebral infarction. Patients were grouped according to identification of a cardiac SOE (106 patients), an arterial SOE (38 patients), or no SOE (49 patients). Cross-tabulations demonstrated that only rapidity and loss of consciousness at onset were associated with the presence of a cardiac SOE to a significant degree. Although these symptoms were highly specific for cardiac SOE, they were not sensitive. A distinct clinical neurologic profile from the symptoms and mode of onset was not identified.
栓塞性中风的诊断基于栓子来源（SOE）的识别以及被视为“临床标准”的神经系统症状。为了检验这些标准的有效性，我们分析了193例急性脑梗死住院患者发病时的症状。根据是否识别出心脏栓子来源（106例患者）、动脉栓子来源（38例患者）或无栓子来源（49例患者）对患者进行分组。交叉表显示，只有发病时的快速性和意识丧失与心脏栓子来源的存在有显著关联。尽管这些症状对心脏栓子来源具有高度特异性，但它们并不敏感。未发现与症状和发病方式不同的临床神经学特征。
