Department of Microelectronics Science and Engineering, Sun Yat-sen University, Guangdong, China.
Stud Health Technol Inform. 2023 Nov 23;308:313-321. doi: 10.3233/SHTI230855.
One of the most prevalent neurological brain diseases is Parkinson's disease, which can be diagnosed a long time ago with a variety of clinical methods. In recent years, it has been common practice to use Electroencephalography (EEG) signal analysis to identify dementia in its early stages because of its high speed, low cost, and accessibility. Many novel methods which apply EEG to the diagnosis of Parkinson's disease are shown to be simple and effective. Recent years have seen the development of EEG signal processing as a key technique for researchers to gather appropriate features for Parkinson's disease diagnosis. In this study, a novel system was created for computer-aided diagnosis that is capable of extracting features from EEG signals and discriminating patients affected by Parkinson's disease. After per processing the EEG data, the Butterworth filter has been used to decompose the signals into four frequency sub-bands. Welch's PSD features were then extracted as the input of supervised machine learning methods-the k-Nearest Neighbor (KNN) to classify EEG features into Parkinson's disease (PD) and healthy controls (HC). The 10-fold cross-validation has been employed to validate the performance of this model. The results achieve 98.82% accuracy, 99.19% sensitivity, and 91.77% specificity, respectively. The acquired findings demonstrate the validity of our strategy and that our diagnosis method is improved when compared to earlier research. At last, this novel method may be a supplementary tool for the clinical diagnosis of Parkinson's disease.
帕金森病是最常见的神经脑疾病之一,可以通过多种临床方法在很久以前进行诊断。近年来,由于其速度快、成本低、易于获取,使用脑电图 (EEG) 信号分析来识别痴呆症的早期阶段已成为一种常见做法。许多应用 EEG 诊断帕金森病的新方法被证明既简单又有效。近年来,脑电图信号处理已发展成为研究人员收集帕金森病诊断合适特征的关键技术。在这项研究中,创建了一个新的计算机辅助诊断系统,能够从 EEG 信号中提取特征并区分帕金森病患者。对 EEG 数据进行预处理后,使用巴特沃斯滤波器将信号分解为四个频带子带。然后提取 Welch 的 PSD 特征作为监督机器学习方法的输入- k-最近邻 (KNN) 将 EEG 特征分类为帕金森病 (PD) 和健康对照组 (HC)。采用 10 倍交叉验证来验证该模型的性能。结果分别达到 98.82%的准确率、99.19%的灵敏度和 91.77%的特异性。所获得的研究结果证明了我们策略的有效性,并且与早期研究相比,我们的诊断方法得到了改进。最后,这种新方法可能是帕金森病临床诊断的辅助工具。