Huang J L, Wang X, Yu F, Li M Y, Tang Y T
Department of Laboratory Medicine, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Maternal and Child Diseases, Ministry of Education, Chengdu 610041, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2023 Nov 6;57(11):1813-1819. doi: 10.3760/cma.j.cn112150-20230322-00217.
The vaginal microbiota is a complex and dynamic environment that plays an important role in the healthy reproduction of women. The mechanism of unexplained infertility is not yet clear, and the imbalance and low stability of vaginal microbiota may be related to unexplained infertility. Taking probiotic composite preparations to restore normal vaginal microbiota may be a safe and natural method for treating unexplained infertility. This article reviews the probiotic composite preparations used in the treatment of unexplained infertility both domestically and internationally, including the isolation site of the bacterial species, the use method of the composite preparation, the course of treatment, and the final therapeutic effect, aiming to provide a basis for the clinical application of probiotic composite preparations in the treatment of unexplained infertility.
阴道微生物群是一个复杂且动态的环境,在女性健康生殖中发挥着重要作用。不明原因不孕症的机制尚不清楚,阴道微生物群的失衡和低稳定性可能与不明原因不孕症有关。服用益生菌复合制剂以恢复正常的阴道微生物群可能是治疗不明原因不孕症的一种安全且天然的方法。本文综述了国内外用于治疗不明原因不孕症的益生菌复合制剂,包括菌种的分离部位、复合制剂的使用方法、疗程以及最终治疗效果,旨在为益生菌复合制剂在治疗不明原因不孕症中的临床应用提供依据。