耳部瘢痕疙瘩:一种创新的三步联合治疗方法。
Ear keloids: An innovative 3-steps combined treatment.
机构信息
Novea Skin Center Avezzano, Avezzano, L'Aquila, Italy.
Surgery and Aesthetic Plastic Surgeon, Torino, Italy.
出版信息
Skin Res Technol. 2023 Nov;29(11):e13506. doi: 10.1111/srt.13506.
INTRODUCTION
An excessive proliferation of fibroblasts and collagen synthesis after an injury may lead to a benign fibrous tumor, known as keloid, which does not regress spontaneously. Earlobes are a very frequent site of onset, since after a trauma (i.e., piercing) keloids may develop either on the helix and on the anterior or posterior lobe, from a few months up to several years after the injury.
OBJECTIVES
To report the effectiveness of a combined protocol of CO2 laser + Dye laser + a portable Blue LED Light medical device for Photobiomodulation Therapy (EmoLED®).
METHODS
Fifty-two patients with a total of 56 ear keloids have been treated in the same session with a single CO2 laser procedure + a pulsed Dye laser procedure with an adjunctive EmoLED® procedure for 3 up to 6 min. A monthly follow-up has been performed with an adjunctive EmoLED® session in case of signs of inflammation.
RESULTS
Among 56 treated keloids, 89.3% of them (50/56) did not recur during a follow-up period (from 6 up to 24 months, mean 16.3 months) while six keloids recurred (6/56, 10.7%) with mild thickening of the scar, thus requiring further treatments.
CONCLUSIONS
Even if an excellent outcome obtained by the synergistic effect of combined laser treatments has already been described (i.e., CO2 laser + Dye Laser), the present study showed the adjuvant procedure with EmoLED® can reduce significantly the risk of keloids recurrences.
简介
损伤后成纤维细胞过度增殖和胶原合成可能导致良性纤维瘤,即瘢痕疙瘩,其不会自发消退。耳垂是发病的一个非常常见的部位,因为在创伤(例如穿孔)后,瘢痕疙瘩可能会在几个月到几年后在耳轮、耳甲腔和耳甲艇以及耳垂的前、后部位出现。
目的
报告 CO2 激光+染料激光+便携式蓝光 LED 光医学设备(EmoLED®)联合光生物调节疗法的疗效。
方法
对 52 例共 56 个耳瘢痕疙瘩患者进行单次 CO2 激光治疗+脉冲染料激光治疗,并在炎症迹象时辅以 EmoLED®治疗 3 至 6 分钟。每月进行一次随访,如出现炎症迹象,则辅以 EmoLED®治疗。
结果
在 56 个治疗的瘢痕疙瘩中,89.3%(50/56)在随访期间(6 至 24 个月,平均 16.3 个月)未复发,而 6 个瘢痕疙瘩(6/56,10.7%)复发,瘢痕仅轻度增厚,因此需要进一步治疗。
结论
尽管联合激光治疗的协同效应已获得良好的效果(即 CO2 激光+染料激光),但本研究表明,EmoLED®辅助治疗可显著降低瘢痕疙瘩复发的风险。