Pincus T, Callahan L F, Bradley L A, Vaughn W K, Wolfe F
Arthritis Rheum. 1986 Dec;29(12):1456-66. doi: 10.1002/art.1780291206.
The Minnesota Multiphasic Personality Inventory (MMPI) scales for Hypochondriasis, Depression, and Hysteria were studied in patients with rheumatoid arthritis (RA). The RA patients showed elevated scores on these scales, and these results are similar to those reported in each of 6 published studies. The elevated MMPI scale scores can be explained largely by 5 "disease-related" MMPI statements which met 2 criteria: they were among 11 of the 117 MMPI statements that two-thirds of rheumatologists predicted would be RA-associated; and RA patients and normal subjects differed significantly in their responses to these statements. The responses of RA patients and normal subjects to most other statements in the MMPI Hypochondriasis, Depression, and Hysteria scales were quite similar. In RA patients, responses to "disease-related" statements were correlated with results of measures of disease activity, which indicates that responses to these MMPI items reflect the severity, as well as the presence, of RA. These findings suggest that new criteria are needed for validation of the MMPI as a clinical tool for the recognition of hypochondriasis, depression, and hysteria in a patient who has RA.
对类风湿性关节炎（RA）患者的明尼苏达多相人格调查表（MMPI）中的疑病、抑郁和癔症量表进行了研究。RA患者在这些量表上得分升高，这些结果与6项已发表研究中的每一项所报告的结果相似。MMPI量表得分升高在很大程度上可以由5条“与疾病相关的 ”MMPI陈述来解释，这些陈述符合两个标准：它们是117条MMPI陈述中的11条，三分之二的风湿病学家预测这些陈述与RA相关；并且RA患者和正常受试者对这些陈述的反应存在显著差异。RA患者和正常受试者对MMPI疑病、抑郁和癔症量表中大多数其他陈述的反应非常相似。在RA患者中，对 “与疾病相关的 ”陈述的反应与疾病活动度测量结果相关，这表明对这些MMPI项目的反应反映了RA的严重程度以及是否存在。这些发现表明，需要新的标准来验证MMPI作为识别患有RA的患者的疑病、抑郁和癔症的临床工具。
