Department of Psychology, Syracuse University.
Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine.
Exp Clin Psychopharmacol. 2024 Jun;32(3):369-378. doi: 10.1037/pha0000692. Epub 2023 Nov 27.
Chronic pain populations exhibit greater prevalence of benzodiazepine (BZD) prescription (vs. the general population) and greater likelihood of BZD use not as prescribed and dependence symptoms. Individuals report taking BZDs for pain relief, potentially contributing to maintenance/escalation of BZD use and hazardous couse with prescription opioids. Identifying cognitive factors underlying pain-BZD use relations represents a critical step toward understanding the role of pain in BZD use trajectories. Outcome expectancies for substance-related analgesia have been implicated in pain-substance use comorbidity (e.g., alcohol), and there is reason to believe these processes may extend to BZD use. The present study aimed to examine psychometric properties of a newly adapted Expectancies for Benzodiazepine Analgesia (EBA) scale and probe associations between EBA scores and prescription opioid use behaviors. Participants were 306 adults (38.9% females) endorsing chronic pain and current BZD prescription who completed an online survey. Results provided initial support for psychometric validity of the EBA: evidence of single-factor structure with good model fit (Bollen-Stine bootstrap = .101), excellent internal consistency (α = .93), and evidence of concurrent validity via correlations with pain variables, likelihood of BZD use not as prescribed, BZD dependence symptoms, and self-reported BZD use for pain relief. Exploratory findings among participants prescribed opioids indicated positive covariation between EBA scores and behaviors associated with higher risk opioid use. This is, to our knowledge, the first study to assess analgesia expectancies for BZD use. BZD analgesic expectancies warrant further study as a treatment target in comorbid pain and BZD use. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
慢性疼痛人群的苯二氮䓬类药物(BZD)处方(与普通人群相比)更为普遍,并且更有可能不按规定使用 BZD 并出现依赖症状。人们报告使用 BZD 来缓解疼痛,这可能导致 BZD 的使用维持/升级,并与处方阿片类药物一起带来危险。确定疼痛与 BZD 使用关系的认知因素是理解疼痛在 BZD 使用轨迹中的作用的关键步骤。物质相关镇痛的预期结果已被牵连到疼痛-物质使用共病(例如,酒精)中,并且有理由相信这些过程可能会扩展到 BZD 使用。本研究旨在检验新改编的苯二氮䓬类药物镇痛预期(EBA)量表的心理测量特性,并探讨 EBA 评分与处方阿片类药物使用行为之间的关联。参与者是 306 名(38.9%为女性)报告慢性疼痛和当前 BZD 处方的成年人,他们完成了一项在线调查。结果初步支持了 EBA 的心理测量有效性:具有良好模型拟合的单因素结构的证据(Bollen-Stine 引导值=0.101),极好的内部一致性(α=0.93),以及与疼痛变量、不按规定使用 BZD 的可能性、BZD 依赖症状以及自我报告的 BZD 缓解疼痛使用的相关性的证据表明同时效度。在开处方阿片类药物的参与者中进行的探索性发现表明,EBA 评分与与更高风险阿片类药物使用相关的行为之间存在正相关。据我们所知,这是评估 BZD 使用镇痛预期的第一项研究。BZD 镇痛预期值得进一步研究,作为共病疼痛和 BZD 使用的治疗靶点。(PsycInfo 数据库记录(c)2024 APA,保留所有权利)。