Liu Wei, Zhao Feng, Shankar Achyut, Maple Carsten, Peter James Dinesh, Kim Byung-Gyu, Slowik Adam, Parameshachari Bidare Divakarachari, Lv Jianhui
IEEE J Biomed Health Inform. 2025 Apr;29(4):2365-2376. doi: 10.1109/JBHI.2023.3336721. Epub 2025 Apr 4.
This study explores the application of explainable artificial intelligence (XAI) in the context of medical image analysis within medical cyber-physical systems (MCPS) to enhance transparency and trustworthiness. Meanwhile, this study proposes an explainable framework that integrates machine learning and knowledge reasoning. The explainability of the model is realized when the framework evolution target feature results and reasoning results are the same and are relatively reliable. However, using these technologies also presents new challenges, including the need to ensure the security and privacy of patient data from Internet of Medical Things (IoMT). Therefore, attack detection is an essential aspect of MCPS security. For the MCPS model with only sensor attacks, the necessary and sufficient conditions for detecting attacks are given based on the definition of sparse observability. The corresponding attack detector and state estimator are designed by assuming that some IoMT sensors are under protection. It is expounded that the IoMT sensors under protection play an important role in improving the efficiency of attack detection and state estimation. The experimental results show that the XAI in the context of medical image analysis within MCPS improves the accuracy of lesion classification, effectively removes low-quality medical images, and realizes the explainability of recognition results. This helps doctors understand the logic of the system's decision-making and can choose whether to trust the results based on the explanation given by the framework.
本研究探讨了可解释人工智能(XAI)在医疗信息物理系统(MCPS)中的医学图像分析背景下的应用,以提高透明度和可信度。同时,本研究提出了一个整合机器学习和知识推理的可解释框架。当框架演化目标特征结果与推理结果相同且相对可靠时,模型的可解释性得以实现。然而,使用这些技术也带来了新的挑战,包括需要确保医疗物联网(IoMT)中患者数据的安全和隐私。因此,攻击检测是MCPS安全的一个重要方面。对于仅存在传感器攻击的MCPS模型,基于稀疏可观测性的定义给出了检测攻击的充要条件。通过假设一些IoMT传感器受到保护,设计了相应的攻击检测器和状态估计器。阐述了受保护的IoMT传感器在提高攻击检测和状态估计效率方面发挥着重要作用。实验结果表明,MCPS中医学图像分析背景下的XAI提高了病变分类的准确性,有效去除了低质量医学图像,并实现了识别结果的可解释性。这有助于医生理解系统决策的逻辑,并可以根据框架给出的解释选择是否信任结果。