不对称酮的合成：α,β-不饱和羧酸与芳基重氮盐的双催化交叉偶联反应
Synthesis of unsymmetrical ketones dual catalysed cross-coupling of α,β-unsaturated carboxylic acids with aryldiazonium salts.
作者信息
Chand Shiv, Sharma Anup Kumar, Pandey Anand Kumar, Singh Krishna Nand
机构信息
Department of Chemistry Institute of Science Banaras Hindu University, Varanasi 221005, India.
出版信息
Chem Commun (Camb). 2023 Dec 14;59(100):14827-14830. doi: 10.1039/d3cc04898e.
PMID:38013486
Abstract
A visible light-enabled synthesis of unsymmetrical ketones has been accomplished by the cross-coupling of α,β-unsaturated carboxylic acids and aryldiazonium salts embracing a synergistic eosin Y and Co(OAc)·4HO catalysis. The reaction involves decarboxylative aerobic CC bond cleavage, and is endowed with the creation of new C-C and C-O bonds with good substrate scope.
摘要
通过α,β-不饱和羧酸与芳基重氮盐的交叉偶联反应，在协同的曙红Y和Co(OAc)₂·4H₂O催化作用下，实现了可见光促进的不对称酮的合成。该反应涉及脱羧需氧C-C键裂解，并能够在良好的底物范围内形成新的C-C键和C-O键。
Zotero 插件