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Subphenotypes in critical illness: a priori biological rationale is key.

作者信息

van Amstel Rombout B E, Cremer Olaf L, van Vught Lonneke A, Bos Lieuwe D J

机构信息

Department of Intensive Care Medicine, Amsterdam UMC, Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Amsterdam UMC, Location University of Amsterdam, Amsterdam, The Netherlands.

出版信息

Intensive Care Med. 2024 Feb;50(2):299-301. doi: 10.1007/s00134-023-07273-8. Epub 2023 Nov 28.

DOI:10.1007/s00134-023-07273-8
PMID:38015264
Abstract
摘要

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Subphenotypes in critical illness: a priori biological rationale is key. Author's reply.危重症中的亚表型：先验生物学原理是关键。作者回复。
Intensive Care Med. 2024 Feb;50(2):302-303. doi: 10.1007/s00134-023-07316-0. Epub 2024 Jan 18.

本文引用的文献

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Exploring disease axes as an alternative to distinct clusters for characterizing sepsis heterogeneity.探索疾病轴作为替代明确聚类的方法，以描述脓毒症异质性。
Intensive Care Med. 2023 Nov;49(11):1349-1359. doi: 10.1007/s00134-023-07226-1. Epub 2023 Oct 4.
2
Identifying molecular phenotypes in sepsis: an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials.鉴定脓毒症的分子表型：两项前瞻性观察队列研究的分析和两项随机对照试验的二次分析。
Lancet Respir Med. 2023 Nov;11(11):965-974. doi: 10.1016/S2213-2600(23)00237-0. Epub 2023 Aug 23.
3
Source-specific host response and outcomes in critically ill patients with sepsis: a prospective cohort study.
脓毒症危重症患者的宿主特异性反应和结局：一项前瞻性队列研究。
Intensive Care Med. 2022 Jan;48(1):92-102. doi: 10.1007/s00134-021-06574-0. Epub 2021 Dec 13.
4
Avoiding common pitfalls when clustering biological data.聚类生物数据时避免常见陷阱。
Sci Signal. 2016 Jun 14;9(432):re6. doi: 10.1126/scisignal.aad1932.
5
International comparisons of intensive care: informing outcomes and improving standards.国际重症监护比较：提高结果和改善标准。
Curr Opin Crit Care. 2012 Dec;18(6):700-6. doi: 10.1097/MCC.0b013e32835914d5.