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越南农村社区 2 型糖尿病患者同伴俱乐部干预可行性研究的预分析/后分析。

Pre-/-post-analyses of a feasibility study of a peer-based club intervention among people living with type 2 diabetes in Vietnam's rural communities.

机构信息

Faculty of Public Health, Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam.

Department of Anthropology, University of Copenhagen, Copenhagen K, Denmark.

出版信息

PLoS One. 2023 Nov 28;18(11):e0290355. doi: 10.1371/journal.pone.0290355. eCollection 2023.

Abstract

OBJECTIVES

Insufficient self-management is a significant barrier for people with type 2 diabetes (T2D) to achieve glycemic control and consequently reduce the risk of acute and long-term diabetes complications, negatively affecting their quality of life and increasing their risk of diabetes-related death. This pre-post study aimed to evaluate whether a peer-based club intervention might reduce glycated hemoglobin from baseline to post-intervention and enhance self-management among people living with T2D in two rural communities in Vietnam.

METHODS

A pre-post study was implemented with 222 adults with T2D residing in two rural communities in Vietnam. We used a structured questionnaire, clinical examination, and glycated hemoglobin to evaluate the possible effects of a diabetes club intervention by comparing Glycated Hemoglobin (HbA1c), Body Mass Index (BMI), Blood Pressure (BP), and diabetes-related self-management behaviors at baseline and post-intervention. The data were analyzed using SPSS 20, applying two related sample tests (Wilcoxon and McNemar test) and a paired-sample t-test at a significance level of less than 0.05.

RESULTS

The findings indicated that after implementation of the intervention, there were no significant statistical differences when comparing pre-and post-intervention levels of the primary outcome HbA1c, but some components of diabetes self-management showed statistically significant improvement.

CONCLUSIONS

After the peer support intervention in a Vietnamese rural community, there was no significant reduction in the primary outcome proportion of patients having an HbA1c less than 7%, but foot care knowledge and practice had improved.

TRIAL REGISTRATION

ClinicalTrials.gov NCT05602441.

摘要

目的

自我管理不足是 2 型糖尿病(T2D)患者实现血糖控制、降低急性和长期糖尿病并发症风险的重大障碍,这会对他们的生活质量产生负面影响,并增加其死于糖尿病相关疾病的风险。本研究旨在评估以同伴为基础的俱乐部干预是否可以降低越南两个农村社区 T2D 患者的糖化血红蛋白(HbA1c)水平,并提高其自我管理能力。

方法

本研究采用前后对照设计,共纳入 222 名居住在越南两个农村社区的 T2D 成年人。我们使用结构化问卷、临床检查和糖化血红蛋白来评估糖尿病俱乐部干预的可能效果,通过比较基线和干预后糖化血红蛋白(HbA1c)、体质量指数(BMI)、血压(BP)和糖尿病相关自我管理行为,评估糖尿病俱乐部干预的可能效果。使用 SPSS 20 软件进行数据分析,应用两相关样本检验(Wilcoxon 和 McNemar 检验)和配对样本 t 检验,检验水准为 0.05。

结果

研究结果表明,在实施干预后,主要结局 HbA1c 的前后比较没有统计学差异,但糖尿病自我管理的某些方面有统计学意义的改善。

结论

在越南农村社区实施同伴支持干预后,HbA1c 水平<7%的患者比例没有显著降低,但足部护理知识和实践有所改善。

试验注册

ClinicalTrials.gov NCT05602441。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81cb/10684024/7b2f63b1f0ee/pone.0290355.g001.jpg

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