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激光原位角膜磨镶术后皮瓣截肢的结果。

Outcomes of Flap Amputation After Laser In Situ Keratomileusis.

机构信息

Department of Ophthalmology, Mayo Clinic, Rochester, MN; and.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.

出版信息

Cornea. 2024 Aug 1;43(8):961-965. doi: 10.1097/ICO.0000000000003440. Epub 2023 Nov 27.

Abstract

PURPOSE

The aim of this study was to describe the indications and outcomes of flap amputation after laser in situ keratomileusis (LASIK) at a referral-based institution.

METHODS

In this retrospective consecutive case series, medical records of patients who underwent LASIK flap amputation at Mayo Clinic, Rochester, MN, between January 1, 1998, and January 31, 2023, were reviewed.

RESULTS

Fifteen eyes (15 patients) underwent flap amputation during the study period. The median age was 45 years (range, 25-71 years), and 8 patients (53%) were men. The median uncorrected visual acuity before flap amputation was 20/200 (range 20/40-hand motions). Indications for flap amputation included epithelial ingrowth (n = 6, 40%), infectious keratitis (n = 6, 40%), diffuse lamellar keratitis (n = 1, 7%), vegetative foreign body (n = 1, 7%), and astigmatism from fixed flap striae (n = 1, 7%). The median duration of follow-up was 8 months (range 1-234 months). Subsequent corneal interventions included chelation of calcific band keratopathy (n = 1, 7%), lamellar keratoplasty (n = 1, 7%), penetrating keratoplasty (n = 2, 18%), keratoprosthesis (n = 1, 7%), and rigid contact lens wear (n = 4, 27%). The final median best visual acuity was 20/25 (range 20/20-20/200). Compared with noninfectious indications for flap amputation, eyes with infectious indications had worse baseline median uncorrected visual acuity (hand motions vs. 20/63, P < 0.001), were more likely to undergo major corneal surgical intervention (50% vs. 11%), and had worse final median best visual acuity (20/50 vs. 20/20, P = 0.018).

CONCLUSIONS

LASIK flap amputation is sometimes necessary to control threatening corneal diseases. Excellent visual outcomes were achieved in most cases, albeit with additional intervention or rigid contact lens wear.

摘要

目的

本研究旨在描述在转诊机构进行的激光原位角膜磨镶术(LASIK)后进行瓣切开术的适应证和结果。

方法

在这项回顾性连续病例系列研究中,对 1998 年 1 月 1 日至 2023 年 1 月 31 日期间在梅奥诊所(Mayo Clinic)接受 LASIK 瓣切开术的患者的病历进行了回顾。

结果

研究期间,15 只眼(15 例患者)行瓣切开术。中位年龄为 45 岁(范围 25-71 岁),8 例(53%)为男性。瓣切开术前未矫正视力的中位数为 20/200(范围 20/40-手动)。瓣切开术的适应证包括上皮内生长(n=6,40%)、感染性角膜炎(n=6,40%)、弥漫性层状角膜炎(n=1,7%)、植物性异物(n=1,7%)和固定瓣条纹引起的散光(n=1,7%)。中位随访时间为 8 个月(范围 1-234 个月)。随后的角膜干预包括钙化带角膜病变螯合(n=1,7%)、板层角膜移植(n=1,7%)、穿透性角膜移植(n=2,18%)、角膜假体(n=1,7%)和硬性透气性角膜接触镜佩戴(n=4,27%)。最终的中位最佳视力为 20/25(范围 20/20-20/200)。与非感染性瓣切开术适应证相比,感染性适应证的眼基线未矫正视力更差(手动 vs. 20/63,P<0.001),更有可能进行主要的角膜手术干预(50% vs. 11%),且最终最佳视力更差(20/50 vs. 20/20,P=0.018)。

结论

LASIK 瓣切开术有时是控制威胁性角膜疾病所必需的。虽然需要额外的干预或佩戴硬性透气性角膜接触镜,但大多数情况下仍能获得良好的视力结果。

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