Centre Universitaire des Maladies Rénales, CHU de Caen, France.
U1086 INSERM - ANTICIPE - Centre Régional de Lutte Contre le Cancer, François Baclesse, Caen, France.
Perit Dial Int. 2024 Nov;44(6):426-433. doi: 10.1177/08968608231210130. Epub 2023 Nov 28.
Cat ownership is common in peritoneal dialysis (PD) patients, even with recent guidelines recommending avoiding domestic animals during PD exchanges to limit the risk of peritonitis due to pet contamination. We analysed the outcomes of patients who experienced cat-related peritonitis compared with those who experienced peritonitis due to other causes.
This retrospective study based on the Registre de Dialyse Peritoneale de Langue Française data analysed the outcomes of 52 patients experiencing cat-related peritonitis from the beginning of the database (1986) until 21 June 2022 compared with those of 208 matched patients experiencing peritonitis due to other causes. A Cox regression model examined the association between cat-related peritonitis and the composite end point of death in PD or transfer to haemodialysis (HD), death in PD and transfer to HD.
Among patients with an episode of cat-related peritonitis, 11 (21.1%) died, 19 (36.5%) were transferred to HD and 11 (21.1%) were transplanted. In the group with other causes of peritonitis, these numbers were 67 (32%), 81 (39%) and 26 (12.5%), respectively. In multivariate survival analysis, age (hazard ratio (HR): 1.39; 95% confidence interval (CI): 1.13-1.70) and use of assisted PD (HR: 4.07; 95% CI: 2.11-7.86) were associated with the risk of death. Having experienced cat-related peritonitis was not significantly associated with any of the three outcomes (death, transfer to HD or PD cessation).
Patients on PD should be aware that cats may cause a peritoneal infection, which results in similar consequences to those of other causes of peritonitis. However, pets at home should not be considered a contraindication to PD.
猫在腹膜透析（PD）患者中很常见，尽管最近的指南建议在 PD 交换期间避免饲养宠物以降低宠物污染引起腹膜炎的风险。我们分析了经历猫相关腹膜炎与经历其他原因腹膜炎的患者的结局。
这项基于法语腹膜透析登记处数据的回顾性研究分析了从数据库开始（1986 年）到 2022 年 6 月 21 日期间经历过猫相关腹膜炎的 52 名患者的结局，与经历过其他原因腹膜炎的 208 名匹配患者的结局进行了比较。Cox 回归模型检查了猫相关腹膜炎与 PD 相关死亡或转血液透析（HD）、PD 死亡和转 HD 的复合终点之间的关联。
在经历过猫相关腹膜炎的患者中，有 11 名（21.1%）死亡，19 名（36.5%）转 HD，11 名（21.1%）移植。在因其他原因发生腹膜炎的患者中，这些数字分别为 67（32%）、81（39%）和 26（12.5%）。在多变量生存分析中，年龄（危险比（HR）：1.39；95%置信区间（CI）：1.13-1.70）和使用辅助 PD（HR：4.07；95% CI：2.11-7.86）与死亡风险相关。经历过猫相关腹膜炎与这三种结局（死亡、转 HD 或 PD 停止）均无显著相关性。
PD 患者应意识到猫可能引起腹膜感染，其后果与其他原因引起的腹膜炎相似。然而，家中的宠物不应被视为 PD 的禁忌。
