Huang Wenxiu, Wang Shoucai, Li Mingzhe, Zhao Longqiang, Peng Mengyu, Kang Chen, Jiang Guangbin, Ji Fanghua
Guangxi Key Laboratory of Electrochemical and Magneto-chemical Functional Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, People's Republic of China.
J Org Chem. 2023 Dec 15;88(24):17511-17520. doi: 10.1021/acs.joc.3c01903. Epub 2023 Nov 29.
Despite the widespread applications of sulfoximines, green and efficient access to functionalized sulfoximines remains a challenge. By employing an electrochemical strategy, we describe an approach for the construction of -aroylsulfoximines, which features a broad substrate scope, mild reaction conditions, safety on a gram scale, and no need for an external oxidant and transition metal catalysts.
尽管磺胺氧化亚胺有着广泛的应用,但实现功能化磺胺氧化亚胺的绿色高效合成仍然是一项挑战。通过采用电化学策略,我们描述了一种构建α-芳酰基磺胺氧化亚胺的方法,该方法具有底物范围广、反应条件温和、克级规模操作安全且无需外部氧化剂和过渡金属催化剂的特点。