Anderson W W, Lewis D V, Swartzwelder H S, Wilson W A
Brain Res. 1986 Nov 19;398(1):215-9. doi: 10.1016/0006-8993(86)91274-6.
The effect of magnesium-free medium on the electrical activity in CA3 of the rat hippocampal slice was examined. Magnesium removal resulted in the development of spontaneous and triggered interictal-like bursting, followed by spontaneous ictal-like events and finally periodic clustered bursts. The ictal-like events consisted of a tonic firing phase and a phase of clustered burst discharges resembling the tonic and clonic phases of seizures. The return to normal medium resulted in spontaneous and triggered interictal-like bursts.
研究了无镁培养基对大鼠海马切片CA3区电活动的影响。去除镁会导致自发和触发的发作间期样爆发的出现，随后是自发的发作样事件，最终是周期性成簇爆发。发作样事件包括一个强直放电阶段和一个类似于癫痫发作强直和阵挛阶段的成簇爆发放电阶段。恢复到正常培养基会导致自发和触发的发作间期样爆发。
