Nudurupati Uma, Narla Terdha, Punihaole David, Ou Yangguang
Department of Chemistry, University of Vermont USA
Department of Pharmacology, University of Vermont USA.
RSC Adv. 2023 Nov 16;13(48):33688-33695. doi: 10.1039/d3ra05119f.
A facile platform derived from deposition of ethynyl linkers on carbon fiber microelectrodes has been developed for sensitive and selective sensing of Cu(ii). This study is the first to demonstrate the successful anodic deposition of ethynyl linkers, specifically 1,4-diethynylbenzene, onto carbon fiber microelectrodes. Multi-scan deposition of DEB on these microelectrodes resulted in an increased sensitivity and selectivity towards Cu(ii) that persists amidst other divalent interferents and displays sustained performance over four days while stored at room temperature. This method can be extended to other ethynyl terminal moieties, thereby creating a versatile chemical platform that will enable improved sensitivity and selectivity for a new frontier of biomarker measurement.
一种通过在碳纤维微电极上沉积乙炔连接体构建的简易平台已被开发出来，用于对铜（II）进行灵敏且选择性的传感。本研究首次证明了乙炔连接体，特别是1,4 - 二乙炔基苯，能够成功阳极沉积在碳纤维微电极上。在这些微电极上多次扫描沉积DEB，提高了对铜（II）的灵敏度和选择性，即使在存在其他二价干扰物的情况下依然如此，并且在室温储存四天期间仍保持稳定性能。该方法可扩展到其他乙炔末端基团，从而创建一个通用的化学平台，有望提高生物标志物测量新领域的灵敏度和选择性。
