Division of Vascular Surgery and Endovascular Therapy, The Johns Hopkins Medical Institutions, Halsted 668, 600 N Wolfe Street, Baltimore, MD, 21287.
Division of Pediatrics, Boston Children's Hospital, Boston, MA.
Semin Vasc Surg. 2023 Dec;36(4):571-578. doi: 10.1053/j.semvascsurg.2023.10.003. Epub 2023 Oct 7.
Rare vascular conditions frequently pose a diagnostic and therapeutic dilemma for health care providers. Several of these conditions have distinct relevance to females populations but, due to their infrequency, there has been little reported on the outcomes of rare vascular conditions specifically in females populations. We performed a literature review of a selection of three rare vascular conditions known to either disproportionately affect females (median arcuate ligament syndrome and fibromuscular dysplasia) or have unique manifestations in females populations (vascular Ehlers-Danlos syndrome). We performed a descriptive review of the literature focused on these three vascular conditions and identified aspects of the current available research describing sex-based differences in prevalence, any pathophysiology explaining the observed sex-based differences, and the contribution of sex to outcomes for each disease process. In addition, considerations for pregnant females with respect to each rare vascular disease process are discussed.
罕见的血管疾病常常给医疗保健提供者带来诊断和治疗上的困境。其中一些疾病与女性群体有明显的相关性，但由于其罕见性，很少有关于女性群体中罕见血管疾病的具体结果的报道。我们对三种已知的罕见血管疾病进行了文献回顾，这些疾病要么不成比例地影响女性（正中弓状韧带综合征和纤维肌性发育不良），要么在女性群体中有独特的表现（血管型埃勒斯-当洛斯综合征）。我们对这三种血管疾病的文献进行了描述性综述，确定了当前研究中描述患病率中基于性别的差异、解释观察到的基于性别的差异的任何病理生理学以及性对每种疾病过程结果的影响的方面。此外，还讨论了每种罕见血管疾病过程中对孕妇的考虑因素。
