法布里病患者使用大麻缓解夜间神经性疼痛。
Relief of nocturnal neuropathic pain with the use of cannabis in a patient with Fabry disease.
作者信息
Bon Martina, Dardis Andrea, Scarpa Maurizio, Sechi Annalisa
机构信息
Regional Coordinating Center for Rare Diseases, University Hospital of Udine, Udine, Italy.
出版信息
Mol Genet Metab Rep. 2023 Oct 6;37:101010. doi: 10.1016/j.ymgmr.2023.101010. eCollection 2023 Dec.
Abstract
Neuropathic pain is one of the most invalidating symptoms in patients with Fabry disease (FD), affecting their quality of life, it is linked to small fiber neuropathy and it may not respond to available disease specific treatments. We report the case of a 32 years old man with classic FD and severe neuropathic pain who, after the failure of several standard pharmaceutical approaches, was treated with medical cannabis with relief of nocturnal pain and sleep improvement.
摘要
神经性疼痛是法布里病（FD）患者最使人衰弱的症状之一，影响他们的生活质量，它与小纤维神经病变有关，并且可能对现有的针对该疾病的治疗方法没有反应。我们报告了一例32岁患有典型FD和严重神经性疼痛的男性病例，在几种标准药物治疗方法均失败后，使用医用大麻进行治疗，夜间疼痛得到缓解，睡眠也有所改善。
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