Department of Nephrology, General Hospital of Western Theater Command, Chengdu, PR China.
Department of Statistics, General Hospital of Western Theater Command, Chengdu, PR China.
Ann Med. 2023;55(2):2286638. doi: 10.1080/07853890.2023.2286638. Epub 2023 Dec 6.
The clinical manifestations of maintenance haemodialysis (MHD) outpatients diagnosed with coronavirus disease 2019 (COVID-19) are highly heterogeneous. They are prone to progress to severe conditions, and they often require hospitalization. To better guide the management of MHD outpatients, this retrospective observational study assessed risk factors for hospitalization of MHD patients after a diagnosis of COVID-19.
The demographic data, comorbidities, laboratory indicators and imaging data of 128 MHD outpatients at our haemodialysis centre with confirmed COVID-19 infection from December 2022 to January 2023 were collected. The relationships between these factors and hospitalization of patients were analyzed.
Among the 128 patients, 25 (19.53%) were hospitalized. One of the 25 inpatients was mechanically ventilated, and two of them died. Multivariate logistic regression analysis showed that the hospitalization rate was correlated with age, comorbid diabetes and peripheral blood lymphocyte count.
Older age, comorbid diabetes and lower lymphocyte count are important risk factors for hospitalization of MHD outpatients after a diagnosis of COVID-19. Focusing on these factors may help in early identification of patients who may need to be admitted due to potential disease progression.
确诊 2019 冠状病毒病(COVID-19)的维持性血液透析(MHD)门诊患者的临床表现高度异质,易进展为重症,常需住院治疗。为更好地指导 MHD 门诊患者的管理,本回顾性观察研究评估了 COVID-19 确诊后 MHD 患者住院的危险因素。
收集了我院血液透析中心 2022 年 12 月至 2023 年 1 月 128 例确诊 COVID-19 的 MHD 门诊患者的人口统计学资料、合并症、实验室指标和影像学数据,并分析了这些因素与患者住院之间的关系。
128 例患者中,25 例(19.53%)住院,其中 1 例接受机械通气,2 例死亡。多因素 logistic 回归分析显示,住院率与年龄、合并糖尿病和外周血淋巴细胞计数相关。
年龄较大、合并糖尿病和淋巴细胞计数较低是 COVID-19 确诊后 MHD 门诊患者住院的重要危险因素。关注这些因素可能有助于早期识别因疾病进展而可能需要住院的患者。