Department of Economics, School of Social Sciences, Mulungushi University, Kabwe, Zambia.
HAND Research Group, School of Medicine and Health Sciences, Mulungushi University, Livingstone Campus, Livingstone, Zambia.
PLoS One. 2023 Dec 7;18(12):e0295401. doi: 10.1371/journal.pone.0295401. eCollection 2023.
Hypertension has in the recent past surfaced as one of the conditions that has a significant impact on workforce productivity in emerging economies. Zambia is no different and has in the recent past recorded increasing cases. Despite the impact of hypertension being of great importance in regards to productivity, we have scarcity of data and studies on hypertension-related Productivity-Adjusted Life-Years (PALYs) in Zambia and Africa at large. This study assessed the impact of hypertension on PALYs lost and socioeconomic factors associated with nonadherence to antihypertensive medication (NATAM).
This was a cross-sectional study of 198 participants from Livingstone University Teaching Hospital and Maramba Clinic situated in Livingstone, Zambia. Structured questionnaires were used to collect data. Productivity index multiplied by years lived was used to calculate PALYs and descriptive statistics were used to summarize sociodemographic, clinical and economic variables. Multivariable logistic regression was used to determine factors associated with NATAM.
The participants had a median age (interquartile range (IQR)) of 49 years (41, 59) and 60.1% (n = 119) were females while 39.9% (n = 79) were male. Our estimated PALYs lost per person due to hypertension were 0.2 (IQR 0.0, 2.7). Cumulative PALYs value lost due to the burden of hypertension was estimated to be at $871,239.58 in gross domestic product (GDP). The prevalence of NATAM was 48% (n = 95). The factors that were significantly associated with NATAM were age (odds ratio (OR) 0.94; 95% confidence interval (CI) 0.90, 0.98), female sex (OR 2.52; 95%CI 1.18, 5.40), self-employment (OR 2.57; 95%CI 1.02, 6.45) and absenteeism from work (OR 3.60; 95%CI 1.16, 11.22).
Findings in our study highlight a high economic loss of PALYs due to hypertension with a potential to impact GDP negatively. We also found that NATAM reduced productivity and income among individuals of working age further impacting PALYs lost due to hypertension. The factors associated with NATAM were age, sex, employment status and absenteeism from work. This study underscores the need for interventions targeting young people, females, self-employed individuals, and absentees at work to improve adherence to antihypertensive drugs in order to reduce PALYs lost due to hypertension.
高血压是新兴经济体中影响劳动力生产力的重要因素之一。赞比亚也不例外,高血压病例呈上升趋势。尽管高血压对生产力的影响非常重要,但我们缺乏赞比亚和整个非洲与高血压相关的生产力调整生命年(PALYs)的数据和研究。本研究评估了高血压对丧失的 PALYs 的影响,以及与未遵医嘱服用抗高血压药物(NATAM)相关的社会经济因素。
这是一项横断面研究,共纳入 198 名来自赞比亚利文斯通大学教学医院和马兰巴诊所的参与者。使用结构化问卷收集数据。使用生产力指数乘以生活年数来计算 PALYs,并使用描述性统计方法总结社会人口统计学、临床和经济变量。使用多变量逻辑回归来确定与 NATAM 相关的因素。
参与者的中位年龄(四分位距(IQR))为 49 岁(41,59),60.1%(n=119)为女性,39.9%(n=79)为男性。我们估计每个人因高血压而丧失的 PALYs 为 0.2(IQR 0.0,2.7)。由于高血压负担而丧失的累积 PALYs 值估计为国内生产总值(GDP)中的 871,239.58 美元。NATAM 的患病率为 48%(n=95)。与 NATAM 显著相关的因素包括年龄(比值比(OR)0.94;95%置信区间(CI)0.90,0.98)、女性(OR 2.52;95%CI 1.18,5.40)、自雇(OR 2.57;95%CI 1.02,6.45)和缺勤(OR 3.60;95%CI 1.16,11.22)。
我们的研究结果强调了高血压导致的 PALYs 大量经济损失,这可能对 GDP 产生负面影响。我们还发现,NATAM 降低了工作年龄个体的生产力和收入,进一步导致高血压导致的 PALYs 丧失。与 NATAM 相关的因素包括年龄、性别、就业状况和缺勤。这项研究强调需要针对年轻人、女性、自雇人员和缺勤人员开展干预措施,以提高抗高血压药物的依从性,从而减少因高血压导致的 PALYs 丧失。