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2010-2021 年非洲服用抗高血压药物患者的药物依从性的流行率及其决定因素：系统评价和荟萃分析。

Prevalence and determinants of medication adherence among patients taking antihypertensive medications in Africa: A systematic review and meta-analysis 2010-2021.

机构信息

College of Nursing, Woosuk University, Wanju-gun, Korea.

Mo-Im Kim Nursing Research Institute, Yonsei University College of Nursing, Seoul, South Korea.

出版信息

Nurs Open. 2023 Jun;10(6):3506-3518. doi: 10.1002/nop2.1613. Epub 2023 Jan 24.

DOI:10.1002/nop2.1613
PMID:36693022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10170912/
Abstract

AIM: This study synthesized the prevalence and determinants of hypertension medication adherence. DESIGN: Systematic review and meta-analysis through systematic search in PUBMED, EMBASE, CINAHL, Cochrane library and Google Scholar, from 2010 to 2021. METHODS: Screening was conducted and reported according to PRISMA criteria, and ten studies identified according to predetermined criteria. The studies were evaluated using the Mixed Method Appraisal Tool. Analysis was done using the narrative synthesis method. Prevalence data were examined using random effects meta-analysis in Comprehensive Meta-Analysis version 3. RESULTS: The overall prevalence of medication adherence was 34.1%, and determinants of medication adherence were the ability to attain hypertension control; hypertension knowledge; and treatment-related factors including belief of the drug efficacy, having commodities, sociocultural and financial-related factors. It is imperative to develop, test and use a comprehensive hypertension medication adherence tool that is culturally congruent to Africa.

摘要

目的：本研究综合了高血压药物治疗依从性的流行率及其决定因素。

设计：通过在 PUBMED、EMBASE、CINAHL、 Cochrane 图书馆和 Google Scholar 中进行系统检索，对 2010 年至 2021 年的文献进行系统评价和荟萃分析。

方法：根据 PRISMA 标准进行筛选，并根据预定标准确定了 10 项研究。使用混合方法评估工具对研究进行评估。使用 Comprehensive Meta-Analysis version 3 中的随机效应荟萃分析方法对流行率数据进行分析。

结果：总体药物治疗依从率为 34.1%，药物治疗依从性的决定因素包括达到高血压控制的能力；高血压知识；以及与治疗相关的因素，包括对药物疗效的信念、拥有商品、社会文化和经济相关因素。开发、测试和使用一种与非洲文化相契合的综合高血压药物治疗依从性工具势在必行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3cc/10170912/89dd6c03feaf/NOP2-10-3506-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3cc/10170912/e0810998a0f7/NOP2-10-3506-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3cc/10170912/89dd6c03feaf/NOP2-10-3506-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3cc/10170912/e0810998a0f7/NOP2-10-3506-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3cc/10170912/89dd6c03feaf/NOP2-10-3506-g002.jpg

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[1]
Prevalence and associated factors of adherence to antihypertensive medication: a nationwide cross-sectional study.

BMC Public Health. 2025-7-3

[2]
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[3]
Interpersonal Factors Influencing Hypertension Control: A Cross-Sectional Study Among Hypertensive Patients in the Ashanti Region, Ghana.

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[4]
Uncontrolled hypertension among adult hypertensive patients in Addis Ababa public hospitals: A cross-sectional study of prevalence and associated factors.

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[5]
Intention to use mobile text message reminders for medication adherence among hypertensive patients in North West Ethiopia: a cross-sectional study.

BMC Health Serv Res. 2024-11-22

[6]
Development of quality indicators for hypertension management at the primary health care level in South Africa.

J Hum Hypertens. 2025-2

[7]
High rate of uncontrolled hypertension among adults receiving integrated HIV and hypertension care with aligned multi-month dispensing in Malawi: results from a cross-sectional survey and retrospective chart review.

J Int AIDS Soc. 2024-9

[8]
Productivity-adjusted life-years and correlates of uncontrolled hypertension at two health facilities in Zambia.

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本文引用的文献

[1]
Adherence to antihypertensive medications and associated factors among hypertensive patients in Ethiopia: Systematic review and meta-analysis.

SAGE Open Med. 2020-12-22

[2]
Regional Patterns and Association Between Obesity and Hypertension in Africa: Evidence From the H3Africa CHAIR Study.

Hypertension. 2020-5

[3]
Assessment of drug therapy problem and associated factors among adult hypertensive patients at Ayder comprehensive specialized hospital, Northern Ethiopia.

Afr Health Sci. 2019-9

[4]
Prevalence and lifestyle-related risk factors of obesity and unrecognized hypertension among bus drivers in Ghana.

Heliyon. 2020-1-6

[5]
Psycho-behavioural factors associated with medication adherence among male out-patients with hypertension in a Ghanaian hospital.

PLoS One. 2020-1-29

[6]
A study on usefulness of modified medication adherence scale in assessing adherence among hypertensive patients.

Perspect Clin Res. 2019

[7]
Maternal and perinatal outcomes among women with hypertensive disorders in pregnancy in Kumasi, Ghana.

PLoS One. 2019-10-4

[8]
Depression and medication-adherence in patients with hypertension attending a tertiary health facility in South-West Nigeria.

Pan Afr Med J. 2019-5-15

[9]
Medication adherence influencing factors-an (updated) overview of systematic reviews.

Syst Rev. 2019-5-10

[10]
Medication adherence and 24-h blood pressure in apparently uncontrolled hypertensive Nigerian patients.

Niger Postgrad Med J. 2019

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