Brown University School of Public Health, Providence, RI, USA; Center for Health Promotion and Health Equity, Brown School of Public Health, Providence, RI, USA.
Brown University School of Public Health, Providence, RI, USA; Center for Health Promotion and Health Equity, Brown School of Public Health, Providence, RI, USA.
Int J Drug Policy. 2024 Jan;123:104271. doi: 10.1016/j.drugpo.2023.104271. Epub 2023 Dec 6.
BACKGROUND: International efforts have reduced the availability of methamphetamine precursors, but its distribution and use continue to rise. Methamphetamine use can lead to short- and long-term adverse effects, including addiction, physical and psychosocial health problems, socioeconomic troubles, incarceration, overdose, and death. Gay, bisexual, and other men who have sex with men (MSM) have been shown to have an elevated prevalence of methamphetamine use. METHODS: We conducted a systematic review and meta-analysis to estimate the prevalence of methamphetamine use among MSM. We searched electronic databases, such as PubMed, for peer-reviewed literature published between 2011 and 2022. Data on methamphetamine use were extracted, including study features, location, study design, sampling method, recruitment period, specific MSM subgroups, prevalence period, and demographics. Employing a random-effects model, we computed the pooled prevalence of methamphetamine use among MSM across two prevalence periods: recent use (i.e., one month, three months, six months, one year) and lifetime use. RESULTS: The systematic review included 56 studies with a total of 25,953 MSM who use methamphetamine. Most studies were conducted in Europe, with the highest prevalence reported in the United Kingdom. The studies primarily used cross-sectional or cohort study designs with convenience sampling. The pooled prevalence rates across recent use (i.e., past month, past three months, past six months, and past year) was 15% (95% CI [11-19%]). Additionally, we pooled lifetime use, which was 23% (95% CI [9-38%]). High heterogeneity (I > 99%) was observed, indicating significant variation. CONCLUSION: This systematic review and meta-analysis provide a pooled prevalence of methamphetamine use among MSM. The analysis accounts for study design, prevalence period, specific MSM subgroups, and geographical areas to estimate methamphetamine use in diverse settings and populations. The review highlights the need for targeted interventions and harm reduction strategies focused on prevention, education, healthcare access, and stakeholder collaboration to address the multifaceted challenges of methamphetamine use among MSM.
背景：国际社会已努力减少冰毒前体的供应，但冰毒的分销和使用仍在继续增加。冰毒使用会导致短期和长期的不良后果，包括上瘾、身心健康问题、社会经济问题、监禁、过量用药和死亡。男同性恋、双性恋和其他与男性发生性关系的男性（MSM）已被证明冰毒使用率较高。
方法：我们进行了系统评价和荟萃分析，以估计 MSM 中冰毒使用的流行率。我们在电子数据库（如 PubMed）中搜索了 2011 年至 2022 年期间发表的同行评议文献。提取了冰毒使用的数据，包括研究特征、地点、研究设计、抽样方法、招募期、特定的 MSM 亚组、流行期和人口统计学。我们采用随机效应模型，计算了 MSM 在两个流行期（最近使用期，即一个月、三个月、六个月和一年；终身使用期）的冰毒使用的总流行率。
结果：系统评价包括 56 项研究，共有 25953 名使用冰毒的 MSM。大多数研究在欧洲进行，其中英国的报告患病率最高。这些研究主要采用横断面或队列研究设计和方便抽样。最近使用期（即过去一个月、过去三个月、过去六个月和过去一年）的合并流行率为 15%（95%CI[11-19%]）。此外，我们还汇总了终身使用情况，其流行率为 23%（95%CI[9-38%]）。观察到高度异质性（I>99%），表明存在显著差异。
结论：本系统评价和荟萃分析提供了 MSM 中冰毒使用的合并流行率。该分析考虑了研究设计、流行期、特定的 MSM 亚组和地理区域，以估计不同环境和人群中的冰毒使用情况。该综述强调需要针对 MSM 中的冰毒使用问题，采取有针对性的干预和减少伤害策略，包括预防、教育、医疗保健获取和利益相关者合作，以应对这一多方面的挑战。
Cochrane Database Syst Rev. 2008-7-16
Cochrane Database Syst Rev. 2011-9-7
Zotero 插件