文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

提高年轻和老年癌症患者生存率的治疗方法。

Therapeutic Approaches to Increase the Survival Rate of Cancer Patients in the Younger and Older Population.

机构信息

Cancer Science Laboratory, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, 603203, Chengalpattu, India.

出版信息

Curr Aging Sci. 2024;17(1):16-30. doi: 10.2174/0118746098241507231127114248.


DOI:10.2174/0118746098241507231127114248
PMID:38062658
Abstract

Various developments have been observed in the treatment of cancer patients, such as higher survival rates and better treatment outcomes. However, expecting similar outcomes in older patients remains a challenge. The main reason for this conclusion is the exclusion of older people from clinical trials for cancer drugs, as well as other factors, such as comorbidity, side effects, age-related frailties and their willingness to undergo multiple treatments. However, the discovery of new techniques and drug combinations has led to a significant improvement in the survival of the elderly population after the onset of the disease. On the other hand, cancer treatments have not become more complex for the younger population when compared to the older population, as the younger population tends to respond well to treatment trials and their physiological conditions are stable in response to treatments. In summary, this review correlates recent cancer treatment strategies and the corresponding responses and survival outcomes of older and younger patients.

摘要

在癌症患者的治疗中观察到了各种进展,例如更高的生存率和更好的治疗结果。然而,期望老年患者获得类似的结果仍然是一个挑战。得出这一结论的主要原因是将老年人排除在癌症药物的临床试验之外,以及其他因素,如合并症、副作用、与年龄相关的脆弱性以及他们接受多次治疗的意愿。然而,新技术和药物组合的发现导致疾病发作后老年人群的生存率显著提高。另一方面,与老年人群相比,年轻人群的癌症治疗并没有变得更加复杂,因为年轻人群往往对治疗试验反应良好,并且他们的生理状况对治疗反应稳定。总之,本综述将癌症治疗策略的最新进展与老年和年轻患者的相应反应和生存结果相关联。

相似文献

[1]
Therapeutic Approaches to Increase the Survival Rate of Cancer Patients in the Younger and Older Population.

Curr Aging Sci. 2024

[2]
Aspects of survival from colorectal cancer in Denmark.

Dan Med J. 2012-4

[3]
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of paclitaxel, docetaxel, gemcitabine and vinorelbine in non-small-cell lung cancer.

Health Technol Assess. 2001

[4]
Effect of age on safety and efficacy of novel cancer drugs investigated in early-phase clinical trials.

Eur J Cancer. 2024-8

[5]
The role of myelopoietic growth factors in managing cancer in the elderly.

Drugs. 2002

[6]
Effect of Age on Clinical Outcomes in Phase 1 Trial Participants.

Cancer Control. 2015-4

[7]
The consequence of undertreating breast cancer in the elderly.

J Am Coll Surg. 2001-6

[8]
Bladder cancer in the elderly.

Urol Oncol. 2009

[9]
[Chances and limitations of chemotherapy in elderly patients].

Internist (Berl). 2010-3

[10]
[The Veneto Region's Registry of Dialysis and Transplantation: 2006-2007 report].

G Ital Nefrol. 2009

本文引用的文献

[1]
Technological advancements in cancer diagnostics: Improvements and limitations.

Cancer Rep (Hoboken). 2023-2

[2]
LncRNAs as biomarkers for predicting radioresistance and survival in cancer: a meta-analysis.

Sci Rep. 2022-11-2

[3]
Gold nanomaterials for optical biosensing and bioimaging.

Nanoscale Adv. 2021-4-14

[4]
Is cancer biology different in older patients?

Lancet Healthy Longev. 2021-10

[5]
Effects and Mechanisms of Curcumin for the Prevention and Management of Cancers: An Updated Review.

Antioxidants (Basel). 2022-7-28

[6]
Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets.

Cancer Cell Int. 2022-8-15

[7]
Age-associated differences in the cancer molecular landscape.

Trends Cancer. 2022-11

[8]
Cancer treatment and survivorship statistics, 2022.

CA Cancer J Clin. 2022-9

[9]
LncRNAs as Theragnostic Biomarkers for Predicting Radioresistance in Cancer: A Systematic Review and Meta-Analysis.

Front Oncol. 2022-5-25

[10]
Association of Healthy Diet and Physical Activity With Breast Cancer: Lifestyle Interventions and Oncology Education.

Front Public Health. 2022

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索