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直肠癌前切除术后保护性回肠造口术的作用及发病率:单中心经验及文献综述

Role and Morbidity of Protective Ileostomy after Anterior Resection for Rectal Cancer: One Centre Experience and Review of Literature.

作者信息

Coco Claudio, Tondolo Vincenzo, Amodio Luca Emanuele, Pafundi Donato Paolo, Marzi Federica, Rizzo Gianluca

机构信息

U.O.C. Chirurgia Generale 2, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.

Digestive and Colo-Rectal Surgery Unit, Ospedale Isola Tiberina-Gemelli Isola, 00186 Rome, Italy.

出版信息

J Clin Med. 2023 Nov 22;12(23):7229. doi: 10.3390/jcm12237229.

Abstract

The creation of a protective stoma is considered a valid life-saving tool, significantly reducing the effects of anastomotic leakage in terms of related morbidity, mortality, and reoperation rate. The aim of this study was to evaluate the impact of a protective loop ileostomy in terms of short- and long-term postoperative morbidity, quantifying the stoma-related complications arising after stoma creation and stoma closure and the risk of permanent stoma. From January 2009 to January 2020, 149 patients with rectal cancer treated by anterior resection and protective ileostomy were enrolled in the study. A total of 113 (75.84%) patients were preoperatively treated with neoadjuvant radiochemotherapy. A clinically relevant anastomotic leak occurred in two patients (1.34%). The postoperative stoma complication rate was 6%. According to the Clavien classification, the stoma-related complication grade was I in seven patients (4.7%) and II in two patients (1.3%). A late stoma-related parastomal hernia occurred in one patient (0.67%). In 129 patients (86.57%), it was possible to close the stoma. Postoperative complications of stoma closure occurred in 12 patients (9.3%). The stoma closure complication grade was I in seven cases (5.43%), II in two cases (1.55%), and ≥3 in three cases (2.33%). Incisional hernia was the only late complication recorded in seven cases (5.42%). The permanent stoma rate was 13.43%. A protective ileostomy has a nonnegligible complication rate, but the rate of severe complications is low. Every effort should be made to clearly identify patients in whom the risk of anastomotic leakage justifies the stoma.

摘要

造保护性造口被认为是一种有效的挽救生命的手段,能显著降低吻合口漏在相关发病率、死亡率及再次手术率方面的影响。本研究的目的是评估保护性袢式回肠造口在术后短期和长期发病率方面的影响,量化造口形成和关闭后出现的与造口相关的并发症以及永久性造口的风险。2009年1月至2020年1月,149例行前切除术及保护性回肠造口术的直肠癌患者纳入本研究。共有113例(75.84%)患者术前接受了新辅助放化疗。2例患者(1.34%)发生了具有临床意义的吻合口漏。术后造口并发症发生率为6%。根据Clavien分级,7例患者(4.7%)的造口相关并发症为I级,2例患者(1.3%)为II级。1例患者(0.67%)发生了晚期造口相关的造口旁疝。129例患者(86.57%)成功关闭了造口。造口关闭术后并发症发生在12例患者(9.3%)中。造口关闭并发症分级为I级7例(5.43%),II级2例(1.55%),≥3级3例(2.33%)。切口疝是7例(5.42%)患者中记录到的唯一晚期并发症。永久性造口率为13.43%。保护性回肠造口术有不可忽视的并发症发生率,但严重并发症发生率较低。应尽一切努力明确哪些患者吻合口漏的风险足以证明造口的合理性。

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