Schroeder W W, Myer C M, Schechter G L
Laryngoscope. 1987 Feb;97(2):131-5. doi: 10.1288/00005537-198702000-00002.
Ectopic gastric mucosa is a known entity of the mid and lower esophagus which was initially described by Schmidt in 1805. The presence of ectopic gastric mucosa in the cervical esophagus, however, was not described. A review of the literature reveals that ectopic gastric mucosa of the cervical esophagus is not uncommon, but symptoms rarely have been attributed to its presence. This paper reports five patients with isolated inflamed ectopic gastric mucosa in the cervical esophagus who presented with odynophagia and/or dysphagia. Physical examination was unremarkable in each case, and an acid barium esophagram was negative in four of five patients. Factors that distinguish these patients from other cases of odynophagia and dysphagia, as well as detailed clinical findings and treatment, are described. Debate exists as to whether the origin of ectopic gastric mucosa is congenital or acquired. The embryology, gross and microscopic anatomy, and pathologic features are outlined. Patients with persistent dysphagia should have flexible fiberoptic esophagoscopy with an index of suspicion to the existence of ectopic gastric mucosa. Inflamed or ulcerated ectopic gastric mucosa in the cervical esophagus should be treated to relieve symptoms and because of the potential for complications.
异位胃黏膜是食管中下段已知的一种病变,最初由施密特于1805年描述。然而,颈段食管存在异位胃黏膜的情况此前未见报道。文献回顾显示,颈段食管异位胃黏膜并不罕见,但症状很少归因于此。本文报告了5例颈段食管孤立性炎症性异位胃黏膜患者,他们均表现为吞咽痛和/或吞咽困难。每例患者体格检查均无异常,5例患者中有4例食管酸钡造影阴性。文中描述了这些患者与其他吞咽痛和吞咽困难病例的区别因素,以及详细的临床发现和治疗方法。关于异位胃黏膜的起源是先天性还是后天性存在争议。文中概述了其胚胎学、大体和微观解剖结构以及病理特征。持续性吞咽困难的患者应进行可弯曲纤维食管镜检查,并怀疑存在异位胃黏膜。颈段食管炎症或溃疡的异位胃黏膜应予以治疗以缓解症状,并预防并发症。