Sahin Gurol, Adas Gokhan, Koc Bora, Akcakaya Adem, Dogan Yasar, Goksel Suha, Yalcin Ozben
Ethica Hospital, Department of Surgery/Istanbul, Turkey;
Bakırkoy Sadi Konuk Training and Research Hospital, Department of Surgery/Istanbul, Turkey;
Int J Biomed Sci. 2014 Jun;10(2):129-35.
In this study we aim to determine the frequency of Inlet Patch (IP) and its association to clinical symptoms and draw attention to be aware of this heterotopic gastric mucosa.
This study was a prospective case series that IP was detected in the upper gastrointestinal endoscopy. Patients with laringopharyngeal reflux symptoms underwent endoscopy between March 2009 and July 2012 in two different institutions. All the biopsies were obtained from if there is the IP lesion and antral or/and gastric mucosa. The data was prospectively evaluated. The prevalence was compared with those of patients that did not determine IP in the study period.
3907 upper gastrointestinal system endoscopy was performed while 123 patients consist of 51 male and 72 female was determined as IP. The prevalence of IP in patiens who underwent upper gastrointestinal endoscopy was 3.14% in our study. The majority of symptoms of those who had IP were laringopharyngeal reflux symptoms. Heterotopic gastric mucosa was fixed in 114 cases while 28 chronic inflammation, 9 esophagitis, 5 intestinal metaplasia, 4 glicogenic acanthosis were obtained as additional findings in pathological examinations.
Heterotopic gastric mucosa in the proximal esophagus is a frequent finding if the endoscopist is aware of this entity. The importance of IP is the increasing number of cases of neoplastic transformation. Symptomatic patients should be treated and should be considered of the complications of heterotopic gastric mucosa.
在本研究中，我们旨在确定食管入口黏膜片（IP）的发生率及其与临床症状的关联，并提请注意这种异位胃黏膜。
本研究是一项前瞻性病例系列研究，通过上消化道内镜检查发现IP。2009年3月至2012年7月期间，在两家不同机构对有咽喉反流症状的患者进行了内镜检查。所有活检均取自存在IP病变处以及胃窦或/和胃黏膜。对数据进行前瞻性评估。将该患病率与研究期间未发现IP的患者的患病率进行比较。
共进行了3907例上消化道系统内镜检查，其中123例患者（51例男性和72例女性）被确定为IP。在我们的研究中，接受上消化道内镜检查的患者中IP的患病率为3.14%。有IP的患者的大多数症状为咽喉反流症状。病理检查中，114例发现异位胃黏膜，另外还发现28例慢性炎症、9例食管炎、5例肠化生、4例糖原棘皮症。
如果内镜医师了解这种情况，食管近端的异位胃黏膜是一种常见发现。IP的重要性在于肿瘤转化病例数量的增加。有症状的患者应接受治疗，并应考虑异位胃黏膜的并发症。
