Pappot Helle, Taarnhøj Gry Assam, Bentsen Line, Friis Rasmus Blechingberg, Bæksted Christina, Christiansen Mille Guldager, Holländer-Mieritz Cecilie, Møller Pia Krause, Rasmussen Ida Marie Lind, Lund-Jacobsen Trine, Stormoen Dag Rune, Tolstrup Lærke K
Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark.
Institute of Clinical Medicine, University of Copenhagen, Denmark.
Comput Struct Biotechnol J. 2023 Dec 3;24:23-30. doi: 10.1016/j.csbj.2023.11.054. eCollection 2024 Dec.
Many studies using Patient-reported outcomes (PRO) data have been conducted to monitor symptoms and health-related quality of life during follow-up after cancer treatment. However new ways of using (e)PROs have emerged. We aimed to explore the Danish landscape of the use of PRO in a research setting, where PRO is used actively in cancer patients undergoing treatment, and give an overview of how it is embraced by patients and clinicians.
A literature search was performed in June 2023, using the keywords Denmark, cancer, and patient-reported outcomes. An expert on literature searches identified the search terms, and double screening was performed at both abstract and screening levels and full-text stage. The software tool Covidence was used.
467 articles were retrieved and 19 studies were included. They described the type of ePRO instrument used and the application of active ePRO i.e. a dialogue tool in the clinical encounter, release of alerts to clinicians, and enhancement of self-management. Finally, a development in the use of active ePROs over time is elucidated and we show how it is embraced by patients and clinicians.
This mini-review gives an overview of how ePRO solutions are tested in oncological research in Denmark and embraced by patients and clinicians. ePRO solutions in a Danish setting seem well-suited for self-management. However, if more impact is warranted, clinicians need to engage in reviewing and using ePROs. Moreover, for successful implementation, the integration of ePROs in electronic health records must be supported by IT specialists and management.
许多使用患者报告结局（PRO）数据的研究已开展，以监测癌症治疗后随访期间的症状及与健康相关的生活质量。然而，使用电子患者报告结局（ePRO）的新方法已经出现。我们旨在探索丹麦在研究环境中使用PRO的情况，其中PRO在接受治疗的癌症患者中得到积极应用，并概述患者和临床医生对它的接受程度。
2023年6月进行了文献检索，使用关键词丹麦、癌症和患者报告结局。一位文献检索专家确定了检索词，并在摘要、筛选和全文阶段进行了双重筛选。使用了软件工具Covidence。
检索到467篇文章，纳入19项研究。这些研究描述了所使用的ePRO工具类型以及主动ePRO的应用，即临床会诊中的对话工具、向临床医生发出警报以及加强自我管理。最后，阐明了主动ePRO随时间的使用发展情况，并展示了患者和临床医生对它的接受程度。
本综述概述了ePRO解决方案在丹麦肿瘤学研究中的测试方式以及患者和临床医生对它的接受情况。丹麦环境中的ePRO解决方案似乎非常适合自我管理。然而，如果需要更大的影响，临床医生需要参与审查和使用ePRO。此外，为成功实施，IT专家和管理层必须支持将ePRO整合到电子健康记录中。
