1,4-丁二醇滥用的后果：综述
Consequences of 1,4-Butanediol Misuse: A Review.
作者信息
Skryabin VYu, Shevtsova YuB, Novoselova E A
机构信息
Skryabin, MD, PhD, associate professor of addiction psychiatry department, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russian Federation.
Shevtsova, MD, PhD, leading researcher, Moscow Research and Practical Centre on Addictions of the Moscow Department of Healthcare, Moscow, Russia.
出版信息
Psychopharmacol Bull. 2023 Dec 4;53(4):48-53.
Gamma-hydroxybutyrate (GHB), along with its precursors, 1,4-butanediol (1,4-BD) and gamma-butyrolactone (GBL), are potent central depressant agents widely illicitly used for their euphoric and relaxant effects. The article presents a review of the literature on the 1,4-BD misuse, the clinical picture of intoxication, development of addiction and delirium. The available evidence shows that 1,4-BD is a substance with its own psychoactive effects, a high addiction potential and potentially severe withdrawal symptoms.
γ-羟基丁酸（GHB）及其前体1,4-丁二醇（1,4-BD）和γ-丁内酯（GBL）是强效中枢抑制剂，因其欣快和放松作用而被广泛非法使用。本文综述了关于1,4-BD滥用、中毒临床表现、成瘾和谵妄发展的文献。现有证据表明，1,4-BD是一种具有自身精神活性作用、高成瘾潜力和潜在严重戒断症状的物质。
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