[¹²⁵I与¹³¹I的比较生物学效应]
[Comparative biological effectiveness of 125I and 131I].
作者信息
Dedov V I, Norets T A, Stepanenko V F
出版信息
Med Radiol (Mosk). 1987 Feb;32(2):45-9.
PMID:3807724
Abstract
An experimental study of comparative biological efficacy of 125I and 131I at equal absorbed doses (2.3 and 13 Gy) in the thyroid of rats showed that the blastomogenic effect of both radionuclides was almost the same. Sex differences were found in the development of long-term consequences (20 mos. after drug administration): breast tumors developed in female rats and thyroid tumors in male rats.
摘要
一项关于 125I 和 131I 在大鼠甲状腺中同等吸收剂量（2.3 和 13 戈瑞）下比较生物学效应的实验研究表明，两种放射性核素的致瘤效应几乎相同。在长期后果的发展中发现了性别差异（给药后 20 个月）：雌性大鼠发生乳腺肿瘤，雄性大鼠发生甲状腺肿瘤。
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