Yamazaki-Nakashimada Marco Antonio, Herrera-Mora Patricia, Mahrx-Bracho Alfonso, López-Herrera Gabriela, Bustamante-Ogando Juan Carlos, Scheffler-Mendoza Selma Cecilia
Department of Pediatric Clinical Immunology, Instituto Nacional de Pediatria. Mexico City, Mexico.
Department of Pediatric Neurology, Instituto Nacional de Pediatria. Mexico City, Mexico.
Iran J Allergy Asthma Immunol. 2023 Oct 29;22(5):504-509. doi: 10.18502/ijaai.v22i5.13999.
Most patients with X-linked agammaglobulinemia are susceptible to infections, while some cases also suffer from inflammatory or autoimmune complications. We describe a patient with progressive encephalitis who improved after the use of immunomodulatory treatment with corticosteroids, fluoxetine, and nitazoxanide. In most of the cases the evolution of the progressive encephalitis is complicated and catastrophic. Based on our experience and the review of the literature, we propose the use of this combined treatment to control this devastating complication.
大多数X连锁无丙种球蛋白血症患者易受感染，而部分病例还会出现炎症或自身免疫并发症。我们描述了一名患有进行性脑炎的患者，在使用皮质类固醇、氟西汀和硝唑尼特进行免疫调节治疗后病情有所改善。在大多数病例中，进行性脑炎的病情发展复杂且具有灾难性。基于我们的经验和文献回顾，我们建议使用这种联合治疗来控制这种毁灭性的并发症。
