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新鲜蔬菜和腌制蔬菜摄入与估算肾小球滤过率的关联。

Association of fresh vegetable and salt-preserved vegetable consumptions with estimated glomerular filtration rate.

机构信息

Medical Big Data Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, No.106, Zhongshan Er Road, Guangzhou, Guangdong, China.

出版信息

BMC Nephrol. 2023 Dec 12;24(1):369. doi: 10.1186/s12882-023-03353-5.

Abstract

OBJECTIVE

This study aimed to investigate the relationship between the consumption of fresh and salt-preserved vegetables and the estimated glomerular filtration rate (eGFR), which requires further research.

METHODS

For this purpose, the data of those subjects who participated in the 2011-2012 and 2014 surveys of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and had biomarker data were selected. Fresh and salt-preserved vegetable consumptions were assessed at each wave. eGFR was assessed using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation based on plasma creatinine. Furthermore, a linear mixed model was used to evaluate associations between fresh/salt-preserved vegetables and eGFR.

RESULTS

The results indicated that the median baseline and follow-up eGFRs were 72.47 mL/min/1.73 m² and 70.26 mL/min/1.73 m², respectively. After applying adjusted linear mixed model analysis to the data, the results revealed that compared to almost daily intake, occasional consumption of fresh vegetables was associated with a lower eGFR (β=-2.23, 95% CI: -4.23, -0.23). Moreover, rare or no consumption of salt-preserved vegetables was associated with a higher eGFR (β = 1.87, 95% CI: 0.12, 3.63) compared to individuals who consumed salt-preserved vegetables daily.

CONCLUSION

Fresh vegetable consumption was direct, whereas intake of salt-preserved vegetables was inversely associated with eGFR among the oldest subjects, supporting the potential benefits of diet-rich fresh vegetables for improving eGFR.

摘要

目的

本研究旨在探讨新鲜蔬菜和腌制蔬菜的消费与估算肾小球滤过率(eGFR)之间的关系,这需要进一步研究。

方法

为此,选择了参加 2011-2012 年和 2014 年中国长寿纵向研究(CLHLS)调查并具有生物标志物数据的受试者的数据。在每个波次评估新鲜和腌制蔬菜的消费。eGFR 是根据血浆肌酐使用慢性肾脏病流行病学合作(CKD-EPI)方程评估的。此外,使用线性混合模型评估新鲜/腌制蔬菜与 eGFR 之间的关联。

结果

结果表明,中位基线和随访 eGFR 分别为 72.47 mL/min/1.73 m²和 70.26 mL/min/1.73 m²。对数据进行调整后的线性混合模型分析后,结果表明与几乎每天摄入相比,偶尔摄入新鲜蔬菜与较低的 eGFR 相关(β=-2.23,95%CI:-4.23,-0.23)。此外,与每天食用腌制蔬菜的人相比,很少或不食用腌制蔬菜与较高的 eGFR 相关(β=1.87,95%CI:0.12,3.63)。

结论

在最年长的受试者中,新鲜蔬菜的摄入与 eGFR 呈直接相关,而腌制蔬菜的摄入与 eGFR 呈负相关,这支持了富含新鲜蔬菜的饮食对改善 eGFR 的潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac80/10717767/a4deeedffe8e/12882_2023_3353_Fig1_HTML.jpg

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