Medical Big Data Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, No.106, Zhongshan Er Road, Guangzhou, Guangdong, China.
BMC Nephrol. 2023 Dec 12;24(1):369. doi: 10.1186/s12882-023-03353-5.
This study aimed to investigate the relationship between the consumption of fresh and salt-preserved vegetables and the estimated glomerular filtration rate (eGFR), which requires further research.
For this purpose, the data of those subjects who participated in the 2011-2012 and 2014 surveys of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and had biomarker data were selected. Fresh and salt-preserved vegetable consumptions were assessed at each wave. eGFR was assessed using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation based on plasma creatinine. Furthermore, a linear mixed model was used to evaluate associations between fresh/salt-preserved vegetables and eGFR.
The results indicated that the median baseline and follow-up eGFRs were 72.47 mL/min/1.73 m² and 70.26 mL/min/1.73 m², respectively. After applying adjusted linear mixed model analysis to the data, the results revealed that compared to almost daily intake, occasional consumption of fresh vegetables was associated with a lower eGFR (β=-2.23, 95% CI: -4.23, -0.23). Moreover, rare or no consumption of salt-preserved vegetables was associated with a higher eGFR (β = 1.87, 95% CI: 0.12, 3.63) compared to individuals who consumed salt-preserved vegetables daily.
Fresh vegetable consumption was direct, whereas intake of salt-preserved vegetables was inversely associated with eGFR among the oldest subjects, supporting the potential benefits of diet-rich fresh vegetables for improving eGFR.
本研究旨在探讨新鲜蔬菜和腌制蔬菜的消费与估算肾小球滤过率(eGFR)之间的关系,这需要进一步研究。
为此,选择了参加 2011-2012 年和 2014 年中国长寿纵向研究(CLHLS)调查并具有生物标志物数据的受试者的数据。在每个波次评估新鲜和腌制蔬菜的消费。eGFR 是根据血浆肌酐使用慢性肾脏病流行病学合作(CKD-EPI)方程评估的。此外,使用线性混合模型评估新鲜/腌制蔬菜与 eGFR 之间的关联。
结果表明,中位基线和随访 eGFR 分别为 72.47 mL/min/1.73 m²和 70.26 mL/min/1.73 m²。对数据进行调整后的线性混合模型分析后,结果表明与几乎每天摄入相比,偶尔摄入新鲜蔬菜与较低的 eGFR 相关(β=-2.23,95%CI:-4.23,-0.23)。此外,与每天食用腌制蔬菜的人相比,很少或不食用腌制蔬菜与较高的 eGFR 相关(β=1.87,95%CI:0.12,3.63)。
在最年长的受试者中,新鲜蔬菜的摄入与 eGFR 呈直接相关,而腌制蔬菜的摄入与 eGFR 呈负相关,这支持了富含新鲜蔬菜的饮食对改善 eGFR 的潜在益处。