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[暴露于内毒素的犬空肠离体肠袢运动活性的变化]

[Changes in the motor activity of an isolated intestinal loop from the jejunum of dogs exposed to an endotoxin].

作者信息

Tsafarov M

出版信息

Eksp Med Morfol. 1979;18(2):76-81.

PMID:380968
Abstract

The author examined the motor activity of an isolated Loop in vivo of founonnarcotised dogs under the conditions of chronic experiments before and after administration of E. coli in dose of 0.1, 0.5, 1.0, and 2.0 mg/body weight. There was inhibition of the movements of the intestinal loop, which was manifested by a reduction of the frequency and amplitude of the intestinal contractions. The inhibition of the motor activity was explained by the disturbances in the circulation and neuro-bunoral control of the intestinal smooth muscle.

摘要

作者在慢性实验条件下,对4只麻醉犬体内分离的肠袢进行了运动活性研究,在给予剂量分别为0.1、0.5、1.0和2.0mg/体重的大肠杆菌之前和之后进行观察。发现肠袢运动受到抑制,表现为肠道收缩频率和幅度降低。运动活性的抑制是由肠道平滑肌的循环和神经-体液控制紊乱所导致的。

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