Siegman-Igra Y, Schwartz D, Alperin H, Konforti N
Scand J Infect Dis. 1986;18(6):511-7. doi: 10.3109/00365548609021655.
90 cases of invasive pneumococcal infection hospitalized during the period 1975-1984 were reviewed. The organism was recovered from blood, cerebrospinal fluid or other normally sterile body fluids. 40 of the patients were adults, most of whom had pneumonia, and 50 were children who had pneumonia, primary bacteremia or meningitis. 90% of the adults and 14% of the children had underlying conditions. Nosocomial infection was remarkably more common among adults (25%), than among children (2%). Mortality was similar to that reported by others: 37% for adults and 10% for children. The most important predictive factors for fatal outcome were: old age (greater than 80), meningeal infection, presence of malignancy or chronic lung disease, and failure to mount leucocytosis. 13% of the strains were moderately resistant to penicillin.
回顾了1975年至1984年期间住院的90例侵袭性肺炎球菌感染病例。该病原体从血液、脑脊液或其他通常无菌的体液中分离出来。40例患者为成人，大多数患有肺炎，50例为儿童，患有肺炎、原发性菌血症或脑膜炎。90%的成人和14%的儿童有基础疾病。医院感染在成人中（25%）比在儿童中（2%）明显更常见。死亡率与其他人报告的相似：成人37%，儿童10%。致命结局的最重要预测因素是：高龄（大于80岁）、脑膜感染、存在恶性肿瘤或慢性肺病以及白细胞增多未出现。13%的菌株对青霉素中度耐药。
