Department of Paediatric Cardiology and Cardiac Surgery, Metromed International Cardiac Centre, Calicut, Kerala, India.
Department of Cardiology, Metromed International Cardiac Centre, Calicut, Kerala, India.
Pediatr Cardiol. 2024 Jan;45(1):121-132. doi: 10.1007/s00246-023-03358-9. Epub 2023 Dec 16.
KONAR-MFO (multifunctional occluder) [Lifetech, Shenzhen, China] was first used in humans in 2013 and received the CE mark in May 2018. As name suggest, it can be use in various(multifunctional) situations in paediatric as well as adults. This is a versatile device with an improved delivery and flexibility which make this device a better option to be use with more comfort and minimum complications. This paper is regarding few rare and complicated lesions, like anomalous origin of coronary artery from pulmonary artery (ALCAPA) device closure, device closure of ventricular septal rupture (VSR) post myocardial infarction in sick elderly and finally device closure of paravalvar leak (PVL)after mitral valve replacement which were treated with this device with excellent results. This study is a retrospective review from a tertiary level dedicated cardiac referral centre in south India. Three cases we are reporting here in which Konar-multifunctional occluders were used in locations other than commoner and regular defects like patent ductus arteriosus, ventricular septal defect etc, over the span of one year between April 2022 and March 2023. Pre-procedure, all patients underwent detailed clinical evaluation followed by transthoracic echocardiography, 12-lead electrocardiogram, and Chest X-ray at the outpatient department. All patients were either symptomatic or had a hemodynamically significant lesion on echocardiography. The decision for transcatheter management was taken after discussing with surgical team in view of either high risk surgery or refusal from patients for surgical options. All patients were followed up post procedure at regular intervals with transthoracic echocardiograms and 12-lead electrocardiograms for a minimum period of 6 months. All these three cases mentioned in our study underwent a complete closure of their respective lesions with no evidence of residual shunt. None of these patients had any major complications, prolonged stay, or any vascular injuries. All patients completed minimum 6-month follow-up and were doing well without any residual flows. First case of ALCAPA, after procedure showed improvement in IVCD, QTc duration and also no significant ischemic changes were noted. Myocardial perfusion scintigraphy was done after 6 months of procedure which showed improvement in contractile function and perfusion of left ventricle. Second case of VSR device closure patient showed immediate significant symptomatic improvement. He was transferred to the coronary care unit, and discharged seven days later. As of now the patient is alive and feeling well with no residual shunt detected by transthoracic echocardiography. No procedure -related complications have been recorded during last two years. Third case of PVL device closure had uneventful recovery from anaesthesia. Prosthetic valve functioned normally during the 5 days of post-procedure hospitalization. The transthoracic 2D- echocardiography performed during follow-up at the end of one month showed no mitral PVL.During follow-up after 1 year, the patient improved symptomatically. Normal prosthetic valve function and no leakage documented on transthoracic echocardiography. Konar-MFO emerging as an important occluder with interesting attributes which makes it a very useful asset to have in catheterizations laboratory.
KONAR-MFO(多用途封堵器)[深圳乐普(深圳)医疗器械有限公司]于 2013 年首次应用于人体,并于 2018 年 5 月获得 CE 标志。顾名思义,它可用于儿科和成人的各种(多功能)情况。这是一种多功能设备,具有改进的输送和灵活性,使其成为一种更好的选择,具有更舒适和最小并发症的使用。本文介绍了一些罕见和复杂的病变,如冠状动脉异常起源于肺动脉(ALCAPA)的装置闭合、心肌梗死后老年患者的室间隔破裂(VSR)的装置闭合以及二尖瓣置换术后的瓣周漏(PVL)的装置闭合,这些病变都用该装置取得了良好的效果。这项研究是在印度南部一家三级心脏专科转诊中心进行的回顾性研究。我们在此报告的三个病例中,Konar-多用途封堵器用于治疗动脉导管未闭、室间隔缺损等常见和常规缺陷以外的位置,跨度为 2022 年 4 月至 2023 年 3 月的一年间。在术前,所有患者均在门诊进行详细的临床评估,随后进行经胸超声心动图、12 导联心电图和胸部 X 线检查。所有患者均有症状或经超声心动图检查存在血流动力学意义的病变。在与外科团队讨论后,根据手术风险高或患者拒绝手术选择,决定进行经导管治疗。所有患者均在术后定期进行经胸超声心动图和 12 导联心电图检查,至少随访 6 个月。我们研究中提到的这三个病例均成功地完成了各自病变的完全闭合,无残余分流的证据。这些患者均无重大并发症、延长住院时间或血管损伤。所有患者均完成了至少 6 个月的随访,情况良好,无残余分流。首例 ALCAPA 患者术后 IVCD、QTc 持续时间改善,无明显缺血性改变。术后 6 个月行心肌灌注闪烁显像,显示左心室收缩功能和灌注改善。第二位 VSR 装置闭合患者症状立即显著改善。他被转至冠心病监护病房,7 天后出院。目前患者存活,感觉良好,经胸超声心动图未发现残余分流。在过去两年中没有记录到与手术相关的并发症。第三位 PVL 装置闭合患者麻醉恢复平稳。术后 5 天住院期间人工瓣膜功能正常。术后 1 个月的经胸二维超声心动图检查显示二尖瓣无 PVL。术后 1 年随访时,患者症状改善。经胸超声心动图未见人工瓣膜功能正常和漏诊。Konar-MFO 作为一种具有有趣属性的重要封堵器出现,使其成为导管实验室中非常有用的工具。