Prakoso Radityo, Ariani Rina, Sembiring Aditya Agita, Mendel Brian, Lilyasari Oktavia
Division of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre of Harapan Kita, Universitas Indonesia, Jakarta, Indonesia.
Division of Non-invasive Diagnostic and Cardiovascular Imaging, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre of Harapan Kita, Universitas Indonesia, Jakarta, Indonesia.
Front Cardiovasc Med. 2025 Jul 2;12:1564232. doi: 10.3389/fcvm.2025.1564232. eCollection 2025.
The complex anatomy of DCSA VSD, its proximity to valvular and conduction tissues, and concerns about radiation and contrast make transcatheter closure particularly challenging in pediatric patients. While zero-fluoroscopy closure was not achievable in this case, we successfully performed zero-contrast transcatheter closure in a baby weighing less than 10 kg. This report highlights the feasibility and early outcomes of this approach at our institution.
An 18-month-old, 9 kg boy with a history of feeding difficulties, failure to thrive, and breathlessness since 14 days of age underwent transcatheter closure of a doubly committed subarterial (DCSA) ventricular septal defect (VSD). Transthoracic echocardiography revealed a 4-5 mm left-to-right shunting VSD with preserved ventricular function. Initial attempts to cross the VSD under zero-fluoroscopy guidance using various catheters were unsuccessful, necessitating fluoroscopic assistance without contrast. A Konar-MF VSD occluder (7/5 mm) was successfully deployed retrogradely, achieving complete defect closure with no residual shunt or valve dysfunction. Post-procedure, the patient remained asymptomatic, with excellent device positioning and no complications noted at follow-up.
This case demonstrates the feasibility of zero-contrast percutaneous DCSA-VSD closure in selected patients weighing less than 10 kg. Further studies are needed to validate its safety and long-term outcomes.
双动脉下型室间隔缺损(DCSA VSD)的解剖结构复杂,与瓣膜和传导组织相邻,且存在辐射和造影剂相关问题,这使得小儿患者的经导管封堵术极具挑战性。虽然本病例无法实现零透视封堵,但我们成功地为一名体重不足10 kg的婴儿实施了零造影剂经导管封堵术。本报告强调了该方法在我们机构的可行性和早期结果。
一名18个月大、体重9 kg的男孩,自14日龄起就有喂养困难、发育不良和呼吸急促的病史,接受了双动脉下型室间隔缺损(DCSA VSD)的经导管封堵术。经胸超声心动图显示一个4-5 mm的左向右分流VSD,心室功能保留。最初尝试在零透视引导下使用各种导管穿过VSD未成功,需要在无造影剂的情况下借助透视辅助。一枚Konar-MF VSD封堵器(7/5 mm)逆行成功置入,实现了缺损完全闭合,无残余分流或瓣膜功能障碍。术后,患者仍无症状,封堵器位置良好,随访未发现并发症。
本病例证明了在体重小于10 kg的特定患者中进行零造影剂经皮DCSA-VSD封堵术的可行性。需要进一步研究以验证其安全性和长期结果。