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骨Paget病中的脊髓压迫:与肉瘤样变性及降钙素治疗的关系

Spinal cord compression in Paget's disease of bone with reference to sarcomatous degeneration and calcitonin treatment.

作者信息

Gruszkiewicz J, Doron Y, Borovich B, Zaaroor M

出版信息

Surg Neurol. 1987 Feb;27(2):117-25. doi: 10.1016/0090-3019(87)90282-5.

DOI:10.1016/0090-3019(87)90282-5
PMID:3810440
Abstract

Four cases of spinal cord compression stemming from Paget's disease of bone tissue are reported. Sarcomatous degeneration was proved in one case and in another one malignancy was deduced by computed tomography (CT) scanning. Clinical and radiologic manifestations as well as surgical management are discussed. The value of CT scanning of the spine as an aid in the evaluation of structural changes and the size of the soft tissue mass in sarcomatous degeneration of the lesion is stressed. After calcitonin administration, alleviation of pain and improvement in neurological status have occurred in two treated patients.

摘要

本文报告了4例因骨组织佩吉特病导致脊髓受压的病例。其中1例经证实发生了肉瘤样变性,另一例通过计算机断层扫描(CT)推断为恶性。文中讨论了其临床和放射学表现以及手术治疗方法。强调了脊柱CT扫描在评估病变肉瘤样变性时结构变化和软组织肿块大小方面的辅助价值。在两名接受治疗的患者中,给予降钙素后疼痛减轻,神经功能状态得到改善。

相似文献

1
Spinal cord compression in Paget's disease of bone with reference to sarcomatous degeneration and calcitonin treatment.骨Paget病中的脊髓压迫:与肉瘤样变性及降钙素治疗的关系
Surg Neurol. 1987 Feb;27(2):117-25. doi: 10.1016/0090-3019(87)90282-5.
2
Paget sarcoma of the spine: Scottish Bone Tumor Registry experience.脊柱佩吉特肉瘤:苏格兰骨肿瘤登记处的经验。
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[Sarcomatous degeneration in Paget's disease of the cervical spine, revealed by a Pancoast-Tobias syndrome].[颈椎佩吉特病中的肉瘤样变性,由潘科斯特 - 托比亚斯综合征揭示]
Rev Rhum Mal Osteoartic. 1973 Feb;40(2):145-8.
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Paget's disease with spinal cord compression. Favourable course after decompression and calcitonin treatment in two cases.
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Spinal artery steal syndrome in Paget's disease of bone.骨Paget病中的脊髓动脉盗血综合征
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Compression of cord by Paget's disease.佩吉特病导致的脊髓受压。
Br Med J. 1973 May 12;2(5862):321-2.
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Paget's disease of the spine: unusual features and complications.脊柱佩吉特病:不寻常特征与并发症
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Spinal-cord syndrome due to non-compressive Paget's disease of bone: a spinal-artery steal phenomenon reversible with calcitonin.非压迫性骨Paget病所致脊髓综合征:一种降钙素可逆转的脊髓动脉盗血现象
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[Radiculomedullary compressions by osteosarcoma and by giant cell tumor of the spine occurring in Paget's disease].[骨肉瘤及脊柱巨细胞瘤在佩吉特病中导致的神经根脊髓压迫症]
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Neurological dysfunction in Paget's disease of the vertebral column.脊柱佩吉特病中的神经功能障碍。
J Neurosurg. 1972 Dec;37(6):661-5. doi: 10.3171/jns.1972.37.6.0661.

引用本文的文献

1
Demographic aspects of Paget's disease of bone in the Negev of southern Israel.以色列南部内盖夫地区骨佩吉特病的人口统计学特征。
Calcif Tissue Int. 1994 Nov;55(5):353-5. doi: 10.1007/BF00299314.
2
Advances in the management of Paget's disease of bone.
Drugs. 1990 Dec;40(6):829-40. doi: 10.2165/00003495-199040060-00005.