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An Innovative Chemical Adherence Test Demonstrates Very High Rates of Nonadherence to Oral Cardio-Metabolic Medications.一项创新的化学依从性测试表明，口服心血管代谢药物的不依从率非常高。
Kidney Int Rep. 2023 Sep 29;8(12):2818-2821. doi: 10.1016/j.ekir.2023.09.033. eCollection 2023 Dec.
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Intentionality in adherence to long-term therapies. Results from an online survey of 3,001 patients with cardio-metabolic pathologiesin France.长期治疗依从性中的意向性。法国3001名患有心脏代谢疾病患者的在线调查结果。
Patient Prefer Adherence. 2021 Aug 11;15:1739-1753. doi: 10.2147/PPA.S318116. eCollection 2021.
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Characteristics associated with nonadherence to medications for hypertension, diabetes, and dyslipidemia among breast cancer survivors.乳腺癌幸存者中与高血压、糖尿病和血脂异常药物治疗依从性不佳相关的特征。
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Descriptive analysis of mail interventions with physicians and patients to improve adherence with antihypertensive and antidiabetic medications in a mixed-model managed care organization of commercial and Medicare members.在一个由商业保险和医疗保险成员组成的混合模式管理式医疗组织中，对针对医生和患者的邮件干预措施进行描述性分析，以提高抗高血压和抗糖尿病药物的依从性。
J Manag Care Pharm. 2011 Jun;17(5):355-66. doi: 10.18553/jmcp.2011.17.5.355.
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Nonadherence to Oral Medications for Chronic Conditions in Breast Cancer Survivors.乳腺癌幸存者慢性疾病口服药物治疗依从性。
J Oncol Pract. 2016 Aug;12(8):e800-9. doi: 10.1200/JOP.2016.011742. Epub 2016 Jul 12.
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The Effect of Opioid Use and Mental Illness on Chronic Disease Medication Adherence in Superutilizers.阿片类药物使用和精神疾病对超高利用率者慢性病药物治疗依从性的影响。
J Manag Care Spec Pharm. 2018 Mar;24(3):198-207. doi: 10.18553/jmcp.2018.24.3.198.
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Nonadherence to Medications for Chronic Conditions and Nonadherence to Adjuvant Hormonal Therapy in Women With Breast Cancer.慢性疾病药物治疗不依从和乳腺癌女性辅助性激素治疗不依从。
JAMA Oncol. 2016 Oct 1;2(10):1326-1332. doi: 10.1001/jamaoncol.2016.1291.
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Adherence to prescribed oral medication in adult patients undergoing chronic hemodialysis: a critical review of the literature.成年慢性血液透析患者口服药物治疗的依从性：文献综述
Eur J Med Res. 2009 May 14;14(5):185-90. doi: 10.1186/2047-783x-14-5-185.
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Assessing medication adherence in the elderly: which tools to use in clinical practice?评估老年人的药物依从性：临床实践中应使用哪些工具？
Drugs Aging. 2005;22(3):231-55. doi: 10.2165/00002512-200522030-00005.
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Nonadherence to Immunosuppressive Medications Following Pediatric Kidney Transplantation Within Full Cost Coverage Health System: Prevalence and Correlates.儿童肾移植后在全额费用覆盖医保体系下免疫抑制剂药物的不依从：流行率及相关因素。
Exp Clin Transplant. 2020 Oct;18(5):577-584. doi: 10.6002/ect.2020.0101.

引用本文的文献

1
Chemical adherence testing in the clinical management of hypertension: a scoping review.高血压临床管理中的化学黏附测试：一项范围综述
Front Pharmacol. 2024 Nov 6;15:1452464. doi: 10.3389/fphar.2024.1452464. eCollection 2024.
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Cardiovascular medication adherence testing in patients living with HIV: A single-centre observational study.HIV 感染者心血管药物治疗依从性检测：一项单中心观察性研究。
HIV Med. 2024 Dec;25(12):1330-1339. doi: 10.1111/hiv.13715. Epub 2024 Sep 24.

本文引用的文献

1
High non-adherence rates to secondary prevention by chemical adherence testing in patients with TIA.短暂性脑缺血发作患者经化学药物依从性检测，其二级预防的不依从率较高。
J Stroke Cerebrovasc Dis. 2022 Sep;31(9):106665. doi: 10.1016/j.jstrokecerebrovasdis.2022.106665. Epub 2022 Jul 25.
2
Nonadherence in Hypertension: How to Develop and Implement Chemical Adherence Testing.高血压患者不遵医嘱：如何制定并实施药物依从性检测。
Hypertension. 2022 Jan;79(1):12-23. doi: 10.1161/HYPERTENSIONAHA.121.17596. Epub 2021 Nov 5.
3
Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.全球、区域和国家慢性肾脏病负担，1990-2017 年：2017 年全球疾病负担研究的系统分析。
Lancet. 2020 Feb 29;395(10225):709-733. doi: 10.1016/S0140-6736(20)30045-3. Epub 2020 Feb 13.
4
Chronic Kidney Disease and Coronary Artery Disease: JACC State-of-the-Art Review.慢性肾脏病与冠状动脉疾病：美国心脏病学会心血管介入治疗学会最新进展综述。
J Am Coll Cardiol. 2019 Oct 8;74(14):1823-1838. doi: 10.1016/j.jacc.2019.08.1017.
5
Prevalence and Disease Burden of Chronic Kidney Disease.慢性肾脏病的患病率和疾病负担。
Adv Exp Med Biol. 2019;1165:3-15. doi: 10.1007/978-981-13-8871-2_1.
6
2018 ESC/ESH Guidelines for the management of arterial hypertension.2018年欧洲心脏病学会/欧洲高血压学会动脉高血压管理指南。
Eur Heart J. 2018 Sep 1;39(33):3021-3104. doi: 10.1093/eurheartj/ehy339.
7
Adherence to medication in patients with chronic kidney disease: a systematic review of qualitative research.慢性肾病患者的药物依从性：定性研究的系统评价
Clin Kidney J. 2018 Aug;11(4):513-527. doi: 10.1093/ckj/sfx140. Epub 2017 Dec 25.
8
Non-adherence to cardiovascular medications.心血管药物治疗不依从。
Eur Heart J. 2014 Dec 7;35(46):3267-76. doi: 10.1093/eurheartj/ehu364. Epub 2014 Sep 28.
9
Physician assessments of medication adherence and decisions to intensify medications for patients with uncontrolled blood pressure: still no better than a coin toss.医生对血压控制不佳患者药物依从性的评估和增加药物剂量的决策：仍然不比抛硬币好。
BMC Health Serv Res. 2012 Aug 21;12:270. doi: 10.1186/1472-6963-12-270.

An Innovative Chemical Adherence Test Demonstrates Very High Rates of Nonadherence to Oral Cardio-Metabolic Medications.

作者信息

Osman Hanad, Lane Dan, Bernieh Dennis, Seidu Samuel, Patel Prashanth, Khunti Kamlesh, Brunskill Nigel J, Xu Gang, Gupta Pankaj

机构信息

Diabetes Research Centre, Department of Population Health Sciences, College of Life Sciences, University of Leicester, Leicester, UK.

Department of Metabolic Medicine and Chemical Pathology University Hospitals of Leicester NHS Trust, Leicester, UK.

出版信息

Kidney Int Rep. 2023 Sep 29;8(12):2818-2821. doi: 10.1016/j.ekir.2023.09.033. eCollection 2023 Dec.

DOI:10.1016/j.ekir.2023.09.033
PMID:38106590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10719591/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d691/10719591/9e13e395c05d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d691/10719591/9e13e395c05d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d691/10719591/9e13e395c05d/gr1.jpg