Karamushka V I, Gruzina T G, Podol'skaia V I, Ul'berg Z R
Ukr Biokhim Zh (1978). 1987 Jan-Feb;59(1):70-5.
The methods of centrifugation and gel-filtration on Sephadexes G-50 and G-150 were used to study the interaction of Bacillus pumilis cell wall glycoprotein component having the molecular weight of 50 kDa (GP-50) with lyposomes from bacterial lipids. GP-50 is shown to sorb on such liposomes and disturb their barrier properties inducing yield of low-molecular label. GP-50 exerts no effect on properties of liposomes from egg lecithin. Electrostatic forces are supposed to play a decisive role in initial acts of GP-50 interactions with lipid phase of microbial envelopes.
采用离心法以及在葡聚糖G - 50和G - 150上进行凝胶过滤的方法，研究了分子量为50 kDa的短小芽孢杆菌细胞壁糖蛋白组分（GP - 50）与细菌脂质来源的脂质体之间的相互作用。结果表明，GP - 50能吸附在这类脂质体上，并干扰其屏障特性，导致低分子标记物的释放。GP - 50对卵磷脂脂质体的性质没有影响。据推测，静电力在GP - 50与微生物包膜脂质相相互作用的初始过程中起决定性作用。
