[Human lactoferrin: isolation of highly purified preparations from human milk, various physico-chemical properties and distribution in normal and tumor tissues].

Two procedures for isolation of lactoferrin are described using ion exchange and immunoaffinity chromatography. Electrophoretic mobility, molecular mass, isoelectric point and other physico-chemical properties of the antigen were studied. Immunodiffusion and immunoperoxidase techniques exhibited presence of the antigen in some tissues containing glandular epithelium as well as a decrease in lactoferrin content in malignization.