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剖宫产术后抗凝治疗引发术中急性肺血栓栓塞致腹直肌鞘血肿:一例报告

Rectus Sheath Hematoma Triggered by Post-cesarean Anticoagulant Therapy for Intraoperative Acute Pulmonary Thromboembolism: A Case Report.

作者信息

Hirata Yuki, Kawamura Hiroshi, Kato Masataka, Ezaka Yukie, Yoshida Yoshio

机构信息

Obstetrics and Gynecology, University of Fukui, Fukui, JPN.

出版信息

Cureus. 2023 Nov 18;15(11):e49034. doi: 10.7759/cureus.49034. eCollection 2023 Nov.

Abstract

Anticoagulant therapy is essential for the prevention or treatment of peripartum venous thromboembolism (VTE). Administration of a therapeutic dose of anticoagulant immediately after cesarean section may result in the formation of a rectus sheath hematoma. A 32-year-old Japanese woman delivered twin neonates by cesarean section at 37 weeks of gestation. After the removal of the placenta, the patient suddenly complained of left anterior chest pain and dyspnea with hypotension and desaturation, requiring the administration of oxygen and vasopressors. Postoperative contrast-enhanced computed tomography (CT) revealed pulmonary embolism and massive right ovarian vein thrombosis (OVT). An inferior vena cava filter was placed and continuous intravenous heparin was started. A rectus sheath hematoma was noted on postoperative day 2 (POD 2). On POD 5, heparin administration was temporarily discontinued because of an enlarged rectus sheath hematoma. Approximately 24 hours later, the hemoglobin level recovered, and heparin administration was resumed. No further expansion of the hematoma was observed. When a rectus sheath hematoma is formed due to treatment with a therapeutic dose of anticoagulant immediately after cesarean section for peripartum VTE, temporary suspension of anticoagulant administration is reasonable to prevent further expansion of the hematoma without fatal complication.

摘要

抗凝治疗对于预防或治疗围产期静脉血栓栓塞症(VTE)至关重要。剖宫产术后立即给予治疗剂量的抗凝剂可能会导致腹直肌鞘血肿的形成。一名32岁的日本女性在妊娠37周时剖宫产分娩了一对双胞胎新生儿。胎盘娩出后,患者突然出现左前胸疼痛、呼吸困难,伴有低血压和血氧饱和度下降,需要给予氧气和血管升压药。术后增强计算机断层扫描(CT)显示肺栓塞和巨大的右卵巢静脉血栓形成(OVT)。放置了下腔静脉滤器并开始持续静脉输注肝素。术后第2天(POD 2)发现腹直肌鞘血肿。在POD 5时,由于腹直肌鞘血肿增大,肝素输注暂时停止。大约24小时后,血红蛋白水平恢复,肝素输注恢复。未观察到血肿进一步扩大。对于围产期VTE剖宫产术后立即使用治疗剂量的抗凝剂导致腹直肌鞘血肿形成的情况,暂时停用抗凝剂以防止血肿进一步扩大且无致命并发症是合理的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40c6/10728606/ab72c983d9c3/cureus-0015-00000049034-i01.jpg

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