Alberius P, Isberg P E
Am J Anat. 1986 Dec;177(4):519-25. doi: 10.1002/aja.1001770410.
The present study was undertaken to elucidate the relationships between craniofacial and long-bone growth. Nine male New Zealand white rabbits received spherical tantalum bone markers in the tibial epiphyses and in the nasal, frontal, and parietal bones. The animals were followed from 30 to 143 days of age. Growth changes were calculated with a roentgen stereometric system, and the results statistically evaluated. Except for the final interval when all variables varied at random, high correlations between tibial and frontonasal or coronal sutural growth were demonstrated; and the respective linear regression lines were homogeneously assembled. The relationship between the tibia and the sagittal suture displayed great variations between individual animals as well as between the suture's parts, although growth at the interfrontal suture was clearly correlated to tibial growth upon exclusion of the time factor. The first principal component of the three neurocranial sutures was calculated and seemed accurately correlated to long-bone growth. The present study concluded that growth at the frontonasal and coronal sutures normally seems to parallel general somatic development, while growth at the sagittal suture appears individually displaced in time. Nevertheless, when the principal component of the combination of the coronal suture and the neurocranial section of the sagittal suture was computed, this was highly correlated to body growth.
本研究旨在阐明颅面骨与长骨生长之间的关系。九只雄性新西兰白兔在胫骨骨骺以及鼻骨、额骨和顶骨植入了球形钽骨标志物。对这些动物从30日龄跟踪至143日龄。使用X线立体测量系统计算生长变化，并对结果进行统计学评估。除了最后一个所有变量随机变化的时间段外，胫骨与额鼻或冠状缝生长之间显示出高度相关性；并且各自的线性回归线均匀分布。胫骨与矢状缝之间的关系在个体动物之间以及缝的不同部分之间表现出很大差异，尽管排除时间因素后，额间缝的生长与胫骨生长明显相关。计算了三条脑颅骨缝的第一主成分，似乎与长骨生长精确相关。本研究得出结论，额鼻缝和冠状缝的生长通常似乎与一般身体发育平行，而矢状缝的生长在时间上似乎存在个体差异。然而，当计算冠状缝和矢状缝脑颅部分组合的主成分时，其与身体生长高度相关。
