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先天性免疫缺陷及在埃塞俄比亚临床免疫学缺乏培训和专业实践的情况下对受影响儿童进行诊断的努力:简要报告。

Inborn Errors of Immunity and Efforts to Diagnose Affected Children in the Absence of Training and Specialty Practice in Clinical Immunology in Ethiopia: a Brief Report.

机构信息

American Medical Center, Addis Ababa, Ethiopia.

Department of Pediatrics and Child Health, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

出版信息

J Clin Immunol. 2023 Dec 22;44(1):11. doi: 10.1007/s10875-023-01605-5.

DOI:10.1007/s10875-023-01605-5
PMID:38129332
Abstract

Four in five children with inborn errors of immunity globally remain undiagnosed. These figures are disproportionally high in low-income countries like Ethiopia. Apart from the inclusion of basic overviews of these disorders in to postgraduate pediatric curricula, little effort has been placed in to establishing clinical immunology training programs. This report summarizes the existing epidemiology of inborn errors of immunity in Ethiopia, unique presentations in Ethiopian children, challenges faced in diagnosing them, and efforts to improve their management.

摘要

全球有五分之四的患有先天性免疫缺陷的儿童尚未得到诊断。在埃塞俄比亚等低收入国家,这一比例不成比例地高。除了在研究生儿科课程中纳入这些疾病的基本概述外,很少有人致力于建立临床免疫学培训计划。本报告总结了埃塞俄比亚先天性免疫缺陷的现有流行病学情况、埃塞俄比亚儿童的独特表现、诊断这些疾病所面临的挑战以及改善其管理的努力。

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Inborn Errors of Immunity and Efforts to Diagnose Affected Children in the Absence of Training and Specialty Practice in Clinical Immunology in Ethiopia: a Brief Report.先天性免疫缺陷及在埃塞俄比亚临床免疫学缺乏培训和专业实践的情况下对受影响儿童进行诊断的努力:简要报告。
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本文引用的文献

1
Case report: Chronic granulomatous disease presenting with early-onset inflammatory bowel disease and normal oxidative burst testing.病例报告:以早发性炎症性肠病为表现且氧化爆发试验正常的慢性肉芽肿病
Front Pediatr. 2023 Jan 11;10:964025. doi: 10.3389/fped.2022.964025. eCollection 2022.
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Allergy Asthma Clin Immunol. 2022 Mar 4;18(1):19. doi: 10.1186/s13223-022-00662-6.
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Primary immunodeficiency diagnosed at autopsy: a case report.
尸检确诊的原发性免疫缺陷:一例报告
BMC Res Notes. 2014 Jul 4;7:425. doi: 10.1186/1756-0500-7-425.
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Effectiveness of measures to eradicate Staphylococcus aureus carriage in patients with community-associated skin and soft-tissue infections: a randomized trial.消除社区相关性皮肤软组织感染患者金黄色葡萄球菌定植的措施的有效性:一项随机试验。
Infect Control Hosp Epidemiol. 2011 Sep;32(9):872-80. doi: 10.1086/661285.
5
Population prevalence of diagnosed primary immunodeficiency diseases in the United States.美国确诊的原发性免疫缺陷疾病的人群患病率。
J Clin Immunol. 2007 Sep;27(5):497-502. doi: 10.1007/s10875-007-9103-1. Epub 2007 Jun 19.