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腰方肌阻滞的术后加速康复(ERAS)路径对微创妇科手术患者的益处:一项回顾性队列研究

Benefits of the Enhanced Recovery After Surgery (ERAS) Pathway With Quadratus Lumborum Blocks for Minimally Invasive Gynecologic Surgery Patients: A Retrospective Cohort Study.

作者信息

Lee Paul S, Brunette Laurie L, Sriprasert Intira, Eloustaz Mohamed, Deshpande Rasika, Adams Crystal, Muderspach Laila, Roman Lynda, Dickerson Shane, Kim Michael P

机构信息

Anesthesiology, University of Southern California, Los Angeles, USA.

Obstetrics and Gynecology, University of Southern California, Los Angeles, USA.

出版信息

Cureus. 2023 Nov 21;15(11):e49183. doi: 10.7759/cureus.49183. eCollection 2023 Nov.

Abstract

STUDY OBJECTIVE

This study aimed to determine the effect of the implementation of the Enhanced Recovery After Surgery (ERAS) protocol among patients receiving minimally invasive gynecologic surgery.

DESIGN AND SETTING

This retrospective cohort study was performed in a tertiary care hospital.

PATIENTS

A total of 328 females who underwent minimally invasive gynecologic surgeries requiring at least one overnight stay at Keck Hospital of University of Southern California (USC), California, USA, from 2016 to 2020 were included in this study.

INTERVENTIONS

The institutional ERAS protocol was implemented in late 2018. A total of 186 patients from 2016 to 2018 prior to the implementation were compared to 142 patients from 2018 to 2020 after the implementation. Intraoperatively, the ERAS group received a multimodal analgesic regimen (including bilateral quadratus lumborum (QL) blocks) and postoperative care geared toward a satisfactory, safe, and expeditious discharge.

MEASUREMENTS AND MAIN RESULTS

The two groups were similar in demographics, except for the shorter surgical time noted in the ERAS group. The median opioid use was significantly less among the ERAS patients compared with the non-ERAS patients on postoperative day 1 (7.5 vs. 14.3 mg; p<0.001) and throughout the hospital stay (17.4 vs. 36.2 mg; p<0.001). The ERAS group also had a shorter median hospital length of stay compared to the non-ERAS group (p<0.01). Among patients with a malignant diagnosis, patients in the ERAS group had significantly less postoperative day 1 and total opioid use and a shorter hospital stay (p<0.01). Within the ERAS group, 20% of the patients did not end up receiving a QL block. Opioid use and length of stay were similar between patients who did and did not receive the QL block.

CONCLUSIONS

The ERAS pathway was associated with a reduction in opioid use postoperatively and a shorter length of hospital stay after minimally invasive gynecologic surgery. There was a more significant decrease in opioid use and hospital length of stay for patients with malignant diagnoses compared to patients with benign diagnoses. Further research can be done to fully delineate the effect of QL blocks in ERAS protocols.

摘要

研究目的

本研究旨在确定实施加速康复外科(ERAS)方案对接受微创妇科手术患者的影响。

设计与背景

本回顾性队列研究在一家三级护理医院进行。

患者

本研究纳入了2016年至2020年期间在美国加利福尼亚州南加州大学凯克医院接受至少需要过夜住院的微创妇科手术的328名女性患者。

干预措施

机构性ERAS方案于2018年末实施。将2016年至2018年实施前的186例患者与2018年至2020年实施后的142例患者进行比较。术中,ERAS组接受多模式镇痛方案(包括双侧腰方肌(QL)阻滞)以及旨在实现满意、安全和快速出院的术后护理。

测量指标与主要结果

两组在人口统计学方面相似,但ERAS组的手术时间较短。与非ERAS组患者相比,ERAS组患者术后第1天(7.5 mg对14.3 mg;p<0.001)以及整个住院期间(17.4 mg对36.2 mg;p<0.001)的阿片类药物使用量中位数显著更低。与非ERAS组相比,ERAS组的住院时间中位数也更短(p<0.01)。在恶性诊断患者中,ERAS组患者术后第1天和阿片类药物总使用量显著更低,住院时间更短(p<0.01)。在ERAS组中,20%的患者最终未接受QL阻滞。接受和未接受QL阻滞的患者之间阿片类药物使用量和住院时间相似。

结论

ERAS路径与微创妇科手术后阿片类药物使用量减少以及住院时间缩短相关。与良性诊断患者相比,恶性诊断患者的阿片类药物使用量和住院时间下降更为显著。可开展进一步研究以全面阐明QL阻滞在ERAS方案中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d5f/10733622/3b7b22c5ac7b/cureus-0015-00000049183-i01.jpg

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