[心得安中毒时舒张期的血流动力学情况]

[Hemodynamic aspect of adiastole in oxprenolol poisoning].

作者信息

Delacour J L, Blanc P L, Wagschal G, Daoudal P

出版信息

Ann Fr Anesth Reanim. 1986;5(5):542-3. doi: 10.1016/s0750-7658(86)80045-4.

Abstract

Self-poisoning with beta-blockers is uncommon but often life-threatening. A 59 year old man was admitted to the ICU after having ingested an estimated dose of 2 g of oxprenolol. Circulatory collapse occurred without pre-existing cardiac failure. Right ventricular haemodynamic data showed adiastole which responded to massive doses of isoprenaline and dopamine. Subsequently the patient recovered normal haemodynamic parameters. This report suggests that right ventricular dysfunction may complicate beta-blocker overdose.

摘要

β受体阻滞剂自服中毒并不常见，但往往危及生命。一名59岁男性摄入约2克氧烯洛尔后被收入重症监护病房。在无既往心力衰竭的情况下发生了循环衰竭。右心室血流动力学数据显示舒张期异常，对大剂量异丙肾上腺素和多巴胺有反应。随后患者恢复了正常的血流动力学参数。本报告提示右心室功能障碍可能是β受体阻滞剂过量中毒的并发症。