Aslan Siran, Al-Smadi Mohammad Walid, Kozma István, Viola Árpad
Department of Neurotraumatology, Semmelweis University, 1081 Budapest, Hungary.
Department of Neurosurgery and Neurotraumatology, Dr. Manninger Jenő National Traumatology Institute, 1081 Budapest, Hungary.
Cancers (Basel). 2023 Dec 7;15(24):5744. doi: 10.3390/cancers15245744.
Spinal metastatic tumors are common and often cause debilitating symptoms. Image-guided percutaneous thermal ablation (IPTA) has gained significant recognition in managing spinal column tumors due to its exceptional precision and effectiveness. Conventional guidance modalities, including computed tomography, fluoroscopy, and ultrasound, have been important in targeting spinal column tumors while minimizing harm to adjacent critical structures. This study presents a novel approach utilizing a fusion of cone beam computed tomography with magnetic resonance imaging to guide percutaneous thermal ablation for four patients with secondary spinal column tumors. The visual analog scale (VAS) evaluated the procedure effectiveness during an 18-month follow-up. Percutaneous vertebroplasty was performed in two cases, and a thermostat was used during all procedures. Imaging was performed using the Stealth Station navigation system Spine 8 (SSS8) and a 1.5T MRI machine. The fusion of CBCT with MRI allowed for precise tumor localization and guidance for thermal ablation. Initial results indicate successful tumor ablation and symptom reduction, emphasizing the potential of CBCT-MRI fusion in spinal column tumor management. This innovative approach is promising in optimizing therapy for secondary spinal column tumors. Further studies are necessary to validate its efficacy and applicability.
脊柱转移性肿瘤很常见,且常常引发使人虚弱的症状。图像引导下经皮热消融术(IPTA)因其卓越的精准性和有效性,在脊柱肿瘤的治疗中获得了广泛认可。传统的引导方式,包括计算机断层扫描、荧光镜检查和超声检查,在定位脊柱肿瘤并将对邻近关键结构的损伤降至最低方面发挥了重要作用。本研究提出了一种新颖的方法,即利用锥形束计算机断层扫描与磁共振成像的融合技术,为4例继发性脊柱肿瘤患者的经皮热消融提供引导。在18个月的随访期间,采用视觉模拟评分法(VAS)评估手术效果。其中2例患者接受了经皮椎体成形术,所有手术过程均使用了恒温器。成像使用的是Stealth Station导航系统Spine 8(SSS8)和一台1.5T磁共振成像仪。锥形束计算机断层扫描与磁共振成像的融合实现了肿瘤的精确定位以及热消融的引导。初步结果表明肿瘤消融成功且症状减轻,凸显了锥形束计算机断层扫描与磁共振成像融合技术在脊柱肿瘤治疗中的潜力。这种创新方法有望优化继发性脊柱肿瘤的治疗。有必要开展进一步研究以验证其疗效和适用性。